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5yq2

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'''Unreleased structure'''
 
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The entry 5yq2 is ON HOLD until Paper Publication
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==Crystal structure of E.coli aminopeptidase N in complex with Puromycin aminonucleoside==
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<StructureSection load='5yq2' size='340' side='right' caption='[[5yq2]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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Authors: Marapaka, A.K., Ganji, R.J., Reddi, R., Addlagatta, A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5yq2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YQ2 FirstGlance]. <br>
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Description: Crystal structure of E.coli aminopeptidase N in complex with Puromycin aminonucleoside
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GMC:(2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL'>GMC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Membrane_alanyl_aminopeptidase Membrane alanyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.2 3.4.11.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yq2 OCA], [http://pdbe.org/5yq2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yq2 RCSB], [http://www.ebi.ac.uk/pdbsum/5yq2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yq2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/AMPN_ECOLI AMPN_ECOLI]] Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation.
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__TOC__
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</StructureSection>
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[[Category: Membrane alanyl aminopeptidase]]
[[Category: Addlagatta, A]]
[[Category: Addlagatta, A]]
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[[Category: Ganji, R.J]]
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[[Category: Ganji, R J]]
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[[Category: Marapaka, A.K]]
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[[Category: Marapaka, A K]]
[[Category: Reddi, R]]
[[Category: Reddi, R]]
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[[Category: Hydrolase]]
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[[Category: M1 class aminopeptidase]]
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[[Category: O-methyl-l-tyrosine]]

Revision as of 12:08, 7 November 2018

Crystal structure of E.coli aminopeptidase N in complex with Puromycin aminonucleoside

5yq2, resolution 1.60Å

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