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3wbk

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==crystal structure analysis of eukaryotic translation initiation factor 5B and 1A complex==
==crystal structure analysis of eukaryotic translation initiation factor 5B and 1A complex==
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<StructureSection load='3wbk' size='340' side='right' caption='[[3wbk]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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<StructureSection load='3wbk' size='340' side='right'caption='[[3wbk]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3wbk]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WBK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WBK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3wbk]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WBK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WBK FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wbi|3wbi]], [[3wbj|3wbj]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wbi|3wbi]], [[3wbj|3wbj]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FUN12, YAL035W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), TIF11, YMR260C, YM8156.02C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FUN12, YAL035W ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), TIF11, YMR260C, YM8156.02C ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wbk OCA], [http://pdbe.org/3wbk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wbk RCSB], [http://www.ebi.ac.uk/pdbsum/3wbk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wbk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wbk OCA], [https://pdbe.org/3wbk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wbk RCSB], [https://www.ebi.ac.uk/pdbsum/3wbk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wbk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IF2P_YEAST IF2P_YEAST]] Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. [[http://www.uniprot.org/uniprot/IF1A_YEAST IF1A_YEAST]] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
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[[https://www.uniprot.org/uniprot/IF2P_YEAST IF2P_YEAST]] Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. [[https://www.uniprot.org/uniprot/IF1A_YEAST IF1A_YEAST]] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3wbk" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3wbk" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Baker's yeast]]
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[[Category: Large Structures]]
[[Category: Ose, T]]
[[Category: Ose, T]]
[[Category: Tanaka, I]]
[[Category: Tanaka, I]]

Revision as of 05:30, 3 August 2022

crystal structure analysis of eukaryotic translation initiation factor 5B and 1A complex

PDB ID 3wbk

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