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4p1o

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==Crystal structure of the Bateman domain of murine magnesium transporter CNNM2 bound to ATP-Mg==
==Crystal structure of the Bateman domain of murine magnesium transporter CNNM2 bound to ATP-Mg==
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<StructureSection load='4p1o' size='340' side='right' caption='[[4p1o]], [[Resolution|resolution]] 3.06&Aring;' scene=''>
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<StructureSection load='4p1o' size='340' side='right'caption='[[4p1o]], [[Resolution|resolution]] 3.06&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4p1o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P1O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4p1o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P1O FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p1f|4p1f]], [[4p1p|4p1p]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1o OCA], [https://pdbe.org/4p1o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p1o RCSB], [https://www.ebi.ac.uk/pdbsum/4p1o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p1o ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cnnm2, Acdp2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1o OCA], [http://pdbe.org/4p1o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p1o RCSB], [http://www.ebi.ac.uk/pdbsum/4p1o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p1o ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CNNM2_MOUSE CNNM2_MOUSE]] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+).<ref>PMID:15899945</ref>
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[https://www.uniprot.org/uniprot/CNNM2_MOUSE CNNM2_MOUSE] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+).<ref>PMID:15899945</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Abascal-Palacios, G]]
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[[Category: Mus musculus]]
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[[Category: Accardi, A]]
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[[Category: Abascal-Palacios G]]
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[[Category: Corral-Rodriguez, M A]]
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[[Category: Accardi A]]
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[[Category: Diercks, T]]
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[[Category: Corral-Rodriguez MA]]
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[[Category: Encinar, J A]]
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[[Category: Diercks T]]
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[[Category: Ereno-Orbea, J]]
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[[Category: Encinar JA]]
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[[Category: Martinez-Cruz, L A]]
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[[Category: Ereno-Orbea J]]
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[[Category: Muller, D]]
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[[Category: Martinez-Cruz LA]]
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[[Category: Oyenarte, I]]
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[[Category: Muller D]]
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[[Category: Spiwok, V]]
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[[Category: Oyenarte I]]
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[[Category: Stuiver, M]]
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[[Category: Spiwok V]]
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[[Category: Terashima, H]]
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[[Category: Stuiver M]]
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[[Category: Acdp]]
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[[Category: Terashima H]]
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[[Category: Cyclin m]]
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[[Category: Hypomagnesemia]]
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[[Category: Magnesium homeostasis]]
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[[Category: Rare disease]]
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[[Category: Transport]]
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[[Category: Transport protein]]
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Revision as of 12:37, 1 February 2023

Crystal structure of the Bateman domain of murine magnesium transporter CNNM2 bound to ATP-Mg

PDB ID 4p1o

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