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4pa5

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==Tgl - a bacterial spore coat transglutaminase - cystamine complex==
==Tgl - a bacterial spore coat transglutaminase - cystamine complex==
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<StructureSection load='4pa5' size='340' side='right' caption='[[4pa5]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
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<StructureSection load='4pa5' size='340' side='right'caption='[[4pa5]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4pa5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacsu Bacsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PA5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PA5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4pa5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PA5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PA5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DHL:2-AMINO-ETHANETHIOL'>DHL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DHL:2-AMINO-ETHANETHIOL'>DHL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p8i|4p8i]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pa5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pa5 OCA], [https://pdbe.org/4pa5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pa5 RCSB], [https://www.ebi.ac.uk/pdbsum/4pa5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pa5 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tgl, yugV, yuxF, BSU31270 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 BACSU])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-glutamine_gamma-glutamyltransferase Protein-glutamine gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.13 2.3.2.13] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pa5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pa5 OCA], [http://pdbe.org/4pa5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pa5 RCSB], [http://www.ebi.ac.uk/pdbsum/4pa5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pa5 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TGL_BACSU TGL_BACSU]] Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links. In wild-type spores at 37 degrees Celsius, tgl mediates the cross-linking of GerQ in higher molecular mass forms, probably in cooperation with YabG.
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[https://www.uniprot.org/uniprot/TGL_BACSU TGL_BACSU] Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links. In wild-type spores at 37 degrees Celsius, tgl mediates the cross-linking of GerQ in higher molecular mass forms, probably in cooperation with YabG.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacsu]]
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[[Category: Bacillus subtilis subsp. subtilis str. 168]]
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[[Category: Protein-glutamine gamma-glutamyltransferase]]
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[[Category: Large Structures]]
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[[Category: Archer, M]]
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[[Category: Archer M]]
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[[Category: Brito, J A]]
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[[Category: Brito JA]]
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[[Category: Carrondo, M A]]
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[[Category: Carrondo MA]]
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[[Category: Fernandes, C G]]
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[[Category: Fernandes CG]]
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[[Category: Henriques, A O]]
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[[Category: Henriques AO]]
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[[Category: Isidro, A]]
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[[Category: Isidro A]]
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[[Category: Lousa, D]]
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[[Category: Lousa D]]
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[[Category: Placido, D]]
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[[Category: Placido D]]
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[[Category: Pohl, J]]
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[[Category: Pohl J]]
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[[Category: Soares, C M]]
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[[Category: Soares CM]]
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[[Category: Baterial spore coat]]
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[[Category: Nlpc/p60 endopeptidase]]
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[[Category: Papain]]
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[[Category: Protein cross-linking]]
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[[Category: Transferase]]
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Revision as of 12:49, 1 February 2023

Tgl - a bacterial spore coat transglutaminase - cystamine complex

PDB ID 4pa5

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