4zof
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Lobenzarit-like inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)== | ==Lobenzarit-like inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)== | ||
| - | <StructureSection load='4zof' size='340' side='right' caption='[[4zof]], [[Resolution|resolution]] 1.80Å' scene=''> | + | <StructureSection load='4zof' size='340' side='right'caption='[[4zof]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4zof]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycta Mycta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZOF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZOF FirstGlance]. <br> | <table><tr><td colspan='2'>[[4zof]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycta Mycta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZOF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZOF FirstGlance]. <br> | ||
| Line 12: | Line 12: | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA). | [[http://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA). | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Phosphoribosyltransferase|Phosphoribosyltransferase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Anthranilate phosphoribosyltransferase]] | [[Category: Anthranilate phosphoribosyltransferase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mycta]] | [[Category: Mycta]] | ||
[[Category: Baker, E N]] | [[Category: Baker, E N]] | ||
Revision as of 12:20, 17 July 2019
Lobenzarit-like inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
| |||||||||||
Categories: Anthranilate phosphoribosyltransferase | Large Structures | Mycta | Baker, E N | Evans, G L | Lott, J S | Structural genomic | Complex | Inhibitor | Lobenzarit-like analogue | Magnesium binding | Phosphoribosylpyrophosphate | Phosphoribosyltransferase | Prpp | Tbsgc | Transferase-transferase inhibitor complex
