5hi6

<StructureSection load='5hi6' size='340' side='right'caption='[[5hi6]], [[Resolution|resolution]] 2.05&Aring;' scene=''>

<table><tr><td colspan='2'>[[5hi6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_CO92 Yersinia pestis CO92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HI6 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.051&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hi6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hi6 OCA], [https://pdbe.org/5hi6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hi6 RCSB], [https://www.ebi.ac.uk/pdbsum/5hi6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hi6 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/A0A3N4BLI0_YERPE A0A3N4BLI0_YERPE] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[ARBA:ARBA00025067][PIRNR:PIRNR000194]

 

*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]

[[Category: Large Structures]]

[[Category: Yersinia pestis CO92]]

[[Category: Anderson WF]]

[[Category: Chang C]]

[[Category: Joachimiak A]]

[[Category: Kim Y]]

[[Category: Makowska-Grzyska M]]

[[Category: Maltseva N]]

[[Category: Mulligan R]]

[[Category: Papazisi L]]