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5kl9

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==Crystal structure of a putative acyl-CoA thioesterase EC709/ECK0725 from Escherichia coli in complex with CoA==
==Crystal structure of a putative acyl-CoA thioesterase EC709/ECK0725 from Escherichia coli in complex with CoA==
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<StructureSection load='5kl9' size='340' side='right' caption='[[5kl9]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
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<StructureSection load='5kl9' size='340' side='right'caption='[[5kl9]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5kl9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Eco57 Eco57]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KL9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KL9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5kl9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7 Escherichia coli O157:H7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KL9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KL9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1s5u|1s5u]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ybgC, Z0904, ECs0771 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83334 ECO57])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kl9 OCA], [https://pdbe.org/5kl9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kl9 RCSB], [https://www.ebi.ac.uk/pdbsum/5kl9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kl9 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kl9 OCA], [http://pdbe.org/5kl9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kl9 RCSB], [http://www.ebi.ac.uk/pdbsum/5kl9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kl9 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/YBGC_ECO57 YBGC_ECO57]] Thioesterase that appears to be involved in phospholipid metabolism. Some specific acyl-ACPs could be physiological substrates. Displays acyl-CoA thioesterase activity on malonyl-CoA in vitro, catalyzing the hydrolysis of the thioester bond (By similarity).
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[https://www.uniprot.org/uniprot/YBGC_ECOLI YBGC_ECOLI] Thioesterase that appears to be involved in phospholipid metabolism. Some specific acyl-ACPs could be physiological substrates. Displays acyl-CoA thioesterase activity on malonyl-CoA in vitro, catalyzing the hydrolysis of the thioester bond.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Eco57]]
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[[Category: Escherichia coli O157:H7]]
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[[Category: Anderson, W F]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Anderson WF]]
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[[Category: Leo, R Di]]
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[[Category: Di Leo R]]
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[[Category: Savchenko, A]]
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[[Category: Savchenko A]]
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[[Category: Skarina, T]]
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[[Category: Skarina T]]
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[[Category: Stogios, P J]]
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[[Category: Stogios PJ]]
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[[Category: Acyl-coa]]
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[[Category: Alpha/beta fold]]
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[[Category: Csgid]]
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[[Category: Hotdog fold]]
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[[Category: Hydrolase]]
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[[Category: Thioesterase]]
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Current revision

Crystal structure of a putative acyl-CoA thioesterase EC709/ECK0725 from Escherichia coli in complex with CoA

PDB ID 5kl9

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