2bpa

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[[Image:2bpa.gif|left|200px]]
[[Image:2bpa.gif|left|200px]]
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{{Structure
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The line below this paragraph, containing "STRUCTURE_2bpa", creates the "Structure Box" on the page.
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|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bpa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpa OCA], [http://www.ebi.ac.uk/pdbsum/2bpa PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2bpa RCSB]</span>
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'''ATOMIC STRUCTURE OF SINGLE-STRANDED DNA BACTERIOPHAGE PHIX174 AND ITS FUNCTIONAL IMPLICATIONS'''
'''ATOMIC STRUCTURE OF SINGLE-STRANDED DNA BACTERIOPHAGE PHIX174 AND ITS FUNCTIONAL IMPLICATIONS'''
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[[Category: Willingmann, P.]]
[[Category: Willingmann, P.]]
[[Category: Xia, D.]]
[[Category: Xia, D.]]
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[[Category: icosahedral virus]]
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[[Category: Icosahedral virus]]
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[[Category: protein-dna complex]]
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[[Category: Protein-dna complex]]
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[[Category: single strand]]
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[[Category: Single strand]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 20:36:25 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:09:42 2008''
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Revision as of 17:36, 3 May 2008

Template:STRUCTURE 2bpa

ATOMIC STRUCTURE OF SINGLE-STRANDED DNA BACTERIOPHAGE PHIX174 AND ITS FUNCTIONAL IMPLICATIONS


Overview

The mechanism of DNA ejection, viral assembly and evolution are related to the structure of bacteriophage phi X174. The F protein forms a T = 1 capsid whose major folding motif is the eight-stranded antiparallel beta barrel found in many other icosahedral viruses. Groups of 5 G proteins form 12 dominating spikes that enclose a hydrophilic channel containing some diffuse electron density. Each G protein is a tight beta barrel with its strands running radially outwards and with a topology similar to that of the F protein. The 12 'pilot' H proteins per virion may be partially located in the putative ion channel. The small, basic J protein is associated with the DNA and is situated in an interior cleft of the F protein. Tentatively, there are three regions of partially ordered DNA structure,

About this Structure

2BPA is a Protein complex structure of sequences from Enterobacteria phage phix174. Full crystallographic information is available from OCA.

Reference

Atomic structure of single-stranded DNA bacteriophage phi X174 and its functional implications., McKenna R, Xia D, Willingmann P, Ilag LL, Krishnaswamy S, Rossmann MG, Olson NH, Baker TS, Incardona NL, Nature. 1992 Jan 9;355(6356):137-43. PMID:1370343 Page seeded by OCA on Sat May 3 20:36:25 2008

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