2btf

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[[Image:2btf.gif|left|200px]]
[[Image:2btf.gif|left|200px]]
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{{Structure
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|PDB= 2btf |SIZE=350|CAPTION= <scene name='initialview01'>2btf</scene>, resolution 2.55&Aring;
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The line below this paragraph, containing "STRUCTURE_2btf", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND= <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ATP:ADENOSINE-5&#39;-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CH3:METHYL+GROUP'>CH3</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene>
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{{STRUCTURE_2btf| PDB=2btf | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2btf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2btf OCA], [http://www.ebi.ac.uk/pdbsum/2btf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2btf RCSB]</span>
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'''THE STRUCTURE OF CRYSTALLINE PROFILIN-BETA-ACTIN'''
'''THE STRUCTURE OF CRYSTALLINE PROFILIN-BETA-ACTIN'''
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[[Category: Rozycki, M D.]]
[[Category: Rozycki, M D.]]
[[Category: Schutt, C E.]]
[[Category: Schutt, C E.]]
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[[Category: acetylation and actin-binding]]
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[[Category: Acetylation and actin-binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 20:46:26 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:11:27 2008''
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Revision as of 17:46, 3 May 2008

Image:2btf.gif

Template:STRUCTURE 2btf

THE STRUCTURE OF CRYSTALLINE PROFILIN-BETA-ACTIN


Overview

The three-dimensional structure of bovine profilin-beta-actin has been solved to 2.55 A resolution by X-ray crystallography. There are several significant local changes in the structure of beta-actin compared with alpha-actin as well as an overall 5 degrees rotation between its two major domains. Actin molecules in the crystal are organized into ribbons through intermolecular contacts like those found in oligomeric protein assemblies. Profilin forms two extensive contacts with the actin ribbon, one of which appears to correspond to the solution contact in vitro.

About this Structure

2BTF is a Protein complex structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

The structure of crystalline profilin-beta-actin., Schutt CE, Myslik JC, Rozycki MD, Goonesekere NC, Lindberg U, Nature. 1993 Oct 28;365(6449):810-6. PMID:8413665 Page seeded by OCA on Sat May 3 20:46:26 2008

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