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5by6

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==Crystal structure of Trichinella spiralis thymidylate synthase complexed with dUMP==
==Crystal structure of Trichinella spiralis thymidylate synthase complexed with dUMP==
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<StructureSection load='5by6' size='340' side='right' caption='[[5by6]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='5by6' size='340' side='right'caption='[[5by6]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5by6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trisp Trisp]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4g9u 4g9u]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BY6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BY6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5by6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichinella_spiralis Trichinella spiralis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4g9u 4g9u]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BY6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BY6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ts, Tsp_03568 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6334 TRISP])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5by6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5by6 OCA], [https://pdbe.org/5by6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5by6 RCSB], [https://www.ebi.ac.uk/pdbsum/5by6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5by6 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5by6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5by6 OCA], [http://pdbe.org/5by6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5by6 RCSB], [http://www.ebi.ac.uk/pdbsum/5by6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5by6 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9NDD3_TRISP Q9NDD3_TRISP]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5by6" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5by6" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thymidylate synthase]]
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[[Category: Large Structures]]
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[[Category: Trisp]]
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[[Category: Trichinella spiralis]]
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[[Category: Dowiercial, A]]
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[[Category: Dowiercial A]]
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[[Category: Fraczyk, T]]
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[[Category: Fraczyk T]]
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[[Category: Jarmula, A]]
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[[Category: Jarmula A]]
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[[Category: Rode, W]]
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[[Category: Rode W]]
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[[Category: Rypniewski, W]]
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[[Category: Rypniewski W]]
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[[Category: Wilk, P]]
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[[Category: Wilk P]]
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[[Category: Methyltransferase]]
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[[Category: Parasitic nematode]]
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[[Category: Protein-ligand complex]]
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[[Category: Transferase]]
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[[Category: Trichinella spirali]]
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Revision as of 06:12, 7 June 2023

Crystal structure of Trichinella spiralis thymidylate synthase complexed with dUMP

PDB ID 5by6

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