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6b0s

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Current revision (14:29, 4 October 2023) (edit) (undo)
 
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==Crystal structure of circumsporozoite protein aTSR domain in complex with 1710 antibody==
==Crystal structure of circumsporozoite protein aTSR domain in complex with 1710 antibody==
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<StructureSection load='6b0s' size='340' side='right' caption='[[6b0s]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='6b0s' size='340' side='right'caption='[[6b0s]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6b0s]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B0S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B0S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6b0s]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B0S FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">csp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b0s OCA], [http://pdbe.org/6b0s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b0s RCSB], [http://www.ebi.ac.uk/pdbsum/6b0s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b0s ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b0s OCA], [https://pdbe.org/6b0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b0s RCSB], [https://www.ebi.ac.uk/pdbsum/6b0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b0s ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CSP_PLAFO CSP_PLAFO] The circumsporozoite protein is the immunodominant surface antigen on the sporozoite (the infective stage of the malaria parasite that is transmitted from the mosquito to the vertebrate host).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6b0s" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6b0s" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
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*[[3D structures of human antibody|3D structures of human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Plafa]]
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[[Category: Large Structures]]
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[[Category: Bosch, A]]
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[[Category: Plasmodium falciparum]]
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[[Category: Julien, J P]]
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[[Category: Bosch A]]
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[[Category: Murugan, R]]
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[[Category: Julien JP]]
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[[Category: Scally, S W]]
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[[Category: Murugan R]]
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[[Category: Triller, G]]
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[[Category: Scally SW]]
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[[Category: Wardemann, H]]
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[[Category: Triller G]]
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[[Category: Alpha thrombospondin type-1 repeat]]
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[[Category: Wardemann H]]
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[[Category: Circumsporozoite protein]]
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[[Category: Immune system]]
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[[Category: Malaria]]
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Current revision

Crystal structure of circumsporozoite protein aTSR domain in complex with 1710 antibody

PDB ID 6b0s

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