2cb2

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[[Image:2cb2.gif|left|200px]]
[[Image:2cb2.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2cb2 |SIZE=350|CAPTION= <scene name='initialview01'>2cb2</scene>, resolution 1.70&Aring;
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The line below this paragraph, containing "STRUCTURE_2cb2", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=AC1:Fe+Binding+Site+For+Chain+F'>AC1</scene>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_2cb2| PDB=2cb2 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cb2 OCA], [http://www.ebi.ac.uk/pdbsum/2cb2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2cb2 RCSB]</span>
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}}
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'''SULFUR OXYGENASE REDUCTASE FROM ACIDIANUS AMBIVALENS'''
'''SULFUR OXYGENASE REDUCTASE FROM ACIDIANUS AMBIVALENS'''
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[[Category: Urich, T.]]
[[Category: Urich, T.]]
[[Category: 2-his-1-carboxylate facial triad]]
[[Category: 2-his-1-carboxylate facial triad]]
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[[Category: acidophilic]]
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[[Category: Acidophilic]]
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[[Category: archaea]]
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[[Category: Archaea]]
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[[Category: biogeochemical sulfur cycle]]
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[[Category: Biogeochemical sulfur cycle]]
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[[Category: compartmentalization]]
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[[Category: Compartmentalization]]
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[[Category: cysteine persulphide]]
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[[Category: Cysteine persulphide]]
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[[Category: extremophile]]
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[[Category: Extremophile]]
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[[Category: icosatetramer]]
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[[Category: Icosatetramer]]
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[[Category: metal-binding]]
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[[Category: Metal-binding]]
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[[Category: mononuclear non-heme iron]]
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[[Category: Mononuclear non-heme iron]]
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[[Category: nano-structure]]
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[[Category: Nano-structure]]
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[[Category: oxidoreductase]]
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[[Category: Oxidoreductase]]
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[[Category: proto-organelle]]
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[[Category: Proto-organelle]]
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[[Category: sulfur oxygenase reductase]]
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[[Category: Sulfur oxygenase reductase]]
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[[Category: thermophilic]]
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[[Category: Thermophilic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 21:37:32 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:18:57 2008''
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Revision as of 18:37, 3 May 2008

Image:2cb2.gif

Template:STRUCTURE 2cb2

SULFUR OXYGENASE REDUCTASE FROM ACIDIANUS AMBIVALENS


Overview

Numerous microorganisms oxidize sulfur for energy conservation and contribute to the global biogeochemical sulfur cycle. We have determined the 1.7 angstrom-resolution structure of the sulfur oxygenase reductase from the thermoacidophilic archaeon Acidianus ambivalens, which catalyzes an oxygen-dependent disproportionation of elemental sulfur. Twenty-four monomers form a large hollow sphere enclosing a positively charged nanocompartment. Apolar channels provide access for linear sulfur species. A cysteine persulfide and a low-potential mononuclear non-heme iron site ligated by a 2-His-1-carboxylate facial triad in a pocket of each subunit constitute the active sites, accessible from the inside of the sphere. The iron is likely the site of both sulfur oxidation and sulfur reduction.

About this Structure

2CB2 is a Single protein structure of sequence from Acidianus ambivalens. Full crystallographic information is available from OCA.

Reference

X-ray Structure of a self-compartmentalizing sulfur cycle metalloenzyme., Urich T, Gomes CM, Kletzin A, Frazao C, Science. 2006 Feb 17;311(5763):996-1000. PMID:16484493 Page seeded by OCA on Sat May 3 21:37:32 2008

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