5kiu
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==VCP-interacting membrane protein (VIMP)== | |
| - | + | <StructureSection load='5kiu' size='340' side='right' caption='[[5kiu]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5kiu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KIU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KIU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kiu OCA], [http://pdbe.org/5kiu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kiu RCSB], [http://www.ebi.ac.uk/pdbsum/5kiu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kiu ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SELS_HUMAN SELS_HUMAN]] Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.<ref>PMID:15215856</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Tang, W K]] | ||
| + | [[Category: Xia, D]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: P97 adaptor protein]] | ||
| + | [[Category: Vcp-interacting membrane protein]] | ||
| + | [[Category: Vimp]] | ||
Revision as of 08:23, 27 December 2017
VCP-interacting membrane protein (VIMP)
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