6ew0

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'''Unreleased structure'''
 
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The entry 6ew0 is ON HOLD until Paper Publication
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==Cryo-EM structure of GDP-microtubule co-polymerised with doublecortin and supplemented with Taxol==
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<StructureSection load='6ew0' size='340' side='right' caption='[[6ew0]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6ew0]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EW0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EW0 FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TA1:TAXOL'>TA1</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ew0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ew0 OCA], [http://pdbe.org/6ew0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ew0 RCSB], [http://www.ebi.ac.uk/pdbsum/6ew0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ew0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/TBB_PIG TBB_PIG]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
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__TOC__
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</StructureSection>
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[[Category: Sus scrofa]]
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[[Category: Manka, S W]]
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[[Category: Gtpase]]
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[[Category: Microtubule]]
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[[Category: Structural protein]]
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[[Category: Taxol]]
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[[Category: Tubulin]]

Revision as of 07:19, 4 July 2018

Cryo-EM structure of GDP-microtubule co-polymerised with doublecortin and supplemented with Taxol

6ew0, resolution 3.80Å

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