6ewy
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==RipA Peptidoglycan hydrolase (Rv1477, Mycobacterium tuberculosis) N-terminal domain== | |
| - | + | <StructureSection load='6ewy' size='340' side='right' caption='[[6ewy]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ewy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EWY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EWY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ewy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ewy OCA], [http://pdbe.org/6ewy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ewy RCSB], [http://www.ebi.ac.uk/pdbsum/6ewy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ewy ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RIPA_MYCTU RIPA_MYCTU]] Peptidoglycan endopeptidase that cleaves the bond between D-glutamate and meso-diaminopimelate. Binds and degrades high-molecular weight peptidoglycan from a number of Actinobacteria; activity is increased in the presence of RpfB and inhibited by PBP1A (ponA1). Required for normal separation of daughter cells after cell division and for cell wall integrity. Required for host cell invasion and intracellular survival in host macrophages.<ref>PMID:16495549</ref> <ref>PMID:17919286</ref> <ref>PMID:18463693</ref> <ref>PMID:20826344</ref> <ref>PMID:21864539</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bourenkov, G]] | ||
[[Category: Guy, J]] | [[Category: Guy, J]] | ||
| - | [[Category: Steiner, E.M]] | ||
| - | [[Category: Bourenkov, G]] | ||
[[Category: Schneider, G]] | [[Category: Schneider, G]] | ||
[[Category: Schnell, R]] | [[Category: Schnell, R]] | ||
| + | [[Category: Steiner, E M]] | ||
| + | [[Category: Periplasmic protein]] | ||
| + | [[Category: Structural protein]] | ||
Revision as of 08:15, 2 May 2018
RipA Peptidoglycan hydrolase (Rv1477, Mycobacterium tuberculosis) N-terminal domain
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