5mbm
From Proteopedia
(Difference between revisions)
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<StructureSection load='5mbm' size='340' side='right' caption='[[5mbm]], [[Resolution|resolution]] 2.76Å' scene=''> | <StructureSection load='5mbm' size='340' side='right' caption='[[5mbm]], [[Resolution|resolution]] 2.76Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5mbm]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MBM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MBM FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5mbm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MBM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MBM FirstGlance]. <br> |
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SCH:S-METHYL-THIO-CYSTEINE'>SCH</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SCH:S-METHYL-THIO-CYSTEINE'>SCH</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTSB, CPSB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_B Cathepsin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.1 3.4.22.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_B Cathepsin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.1 3.4.22.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mbm OCA], [http://pdbe.org/5mbm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mbm RCSB], [http://www.ebi.ac.uk/pdbsum/5mbm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mbm ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mbm OCA], [http://pdbe.org/5mbm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mbm RCSB], [http://www.ebi.ac.uk/pdbsum/5mbm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mbm ProSAT]</span></td></tr> | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN]] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. | [[http://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN]] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Cathepsin|Cathepsin]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Cathepsin B]] | [[Category: Cathepsin B]] | ||
| + | [[Category: Human]] | ||
| + | [[Category: Synthetic construct sequences]] | ||
[[Category: Kramer, L]] | [[Category: Kramer, L]] | ||
[[Category: Renko, M]] | [[Category: Renko, M]] | ||
Revision as of 07:22, 21 February 2019
Cathepsin B in complex with DARPin 8h6
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Categories: Cathepsin B | Human | Synthetic construct sequences | Kramer, L | Renko, M | Turk, B | Turk, D | Complex | Darpin | Hydrolase | Protease
