6fax

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m (Protected "6fax" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6fax is ON HOLD until Paper Publication
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==Complex of Human CD40 Ectodomain with Lob 7.4 Fab==
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<StructureSection load='6fax' size='340' side='right' caption='[[6fax]], [[Resolution|resolution]] 2.99&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6fax]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FAX FirstGlance]. <br>
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Description:
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fax OCA], [http://pdbe.org/6fax PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fax RCSB], [http://www.ebi.ac.uk/pdbsum/6fax PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fax ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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== Disease ==
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[[http://www.uniprot.org/uniprot/TNR5_HUMAN TNR5_HUMAN]] Defects in CD40 are the cause of immunodeficiency with hyper-IgM type 3 (HIGM3) [MIM:[http://omim.org/entry/606843 606843]]. A rare immunodeficiency syndrome characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE. It results in a profound susceptibility to bacterial infections.<ref>PMID:11675497</ref>
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== Function ==
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[[http://www.uniprot.org/uniprot/TNR5_HUMAN TNR5_HUMAN]] Receptor for TNFSF5/CD40LG.
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Orr, C M]]
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[[Category: Pearson, A R]]
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[[Category: Tews, I]]
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[[Category: Agonist]]
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[[Category: Cd40]]
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[[Category: Engineered fab]]
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[[Category: Immune system]]
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[[Category: Mab]]

Revision as of 06:24, 7 February 2018

Complex of Human CD40 Ectodomain with Lob 7.4 Fab

6fax, resolution 2.99Å

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