Cathepsin
From Proteopedia
(Difference between revisions)
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**[[2ipp]], [[1huc]] – hMCTSB<br /> | **[[2ipp]], [[1huc]] – hMCTSB<br /> | ||
**[[3cbj]], [[3cbk]] – hMCTSB (mutant)+chagasin<br /> | **[[3cbj]], [[3cbk]] – hMCTSB (mutant)+chagasin<br /> | ||
| + | **[[5mbl]], [[5mbm]] – hMCTSB + darpin <br /> | ||
| + | **[[6ay2]] – hMCTSB + inhibitor <br /> | ||
**[[2dc6]], [[2dc7]], [[2dc8]], [[2dc9]], [[2dca]], [[2dcb]], [[2dcc]], [[2dcd]] – bMCTSB+inhibitor – bovine<br /> | **[[2dc6]], [[2dc7]], [[2dc8]], [[2dc9]], [[2dca]], [[2dcb]], [[2dcc]], [[2dcd]] – bMCTSB+inhibitor – bovine<br /> | ||
**[[1sp4]], [[1csb]] – bMCTSB+epoxysuccinyl inhibitor<br /> | **[[1sp4]], [[1csb]] – bMCTSB+epoxysuccinyl inhibitor<br /> | ||
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**[[1yk8]] - hMCTSK + cyanamide inhibitor<br /> | **[[1yk8]] - hMCTSK + cyanamide inhibitor<br /> | ||
**[[1yt7]] - hMCTSK + ketoamide inhibitor<br /> | **[[1yt7]] - hMCTSK + ketoamide inhibitor<br /> | ||
| + | **[[4x6j]] - hMCTSK + benzamide inhibitor<br /> | ||
**[[2aux]], [[2auz]] - hMCTSK + semicarbazone inhibitor<br /> | **[[2aux]], [[2auz]] - hMCTSK + semicarbazone inhibitor<br /> | ||
**[[1ayu]], [[1ayv]], [[1ayw]] - hMCTSK + carbohydrazide inhibitor<br /> | **[[1ayu]], [[1ayv]], [[1ayw]] - hMCTSK + carbohydrazide inhibitor<br /> | ||
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**[[1u9v]], [[1u9x]], [[1mem]] – hMCTSK+piperazine inhibitor<br /> | **[[1u9v]], [[1u9x]], [[1mem]] – hMCTSK+piperazine inhibitor<br /> | ||
**[[1u9w]] - hMCTSK+imidazole inhibitor<br /> | **[[1u9w]] - hMCTSK+imidazole inhibitor<br /> | ||
| - | **[[5tdi]] – hMCTSK + odanacatib<br /> | + | **[[5tdi]], [[4yv8]] – hMCTSK + odanacatib<br /> |
**[[5tdi]] – hMCTSK + lichostatinal<br /> | **[[5tdi]] – hMCTSK + lichostatinal<br /> | ||
**[[5ja7]] – hMCTSK (mutant) + effector<br /> | **[[5ja7]] – hMCTSK (mutant) + effector<br /> | ||
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**[[3h89]], [[3h8b]], [[3h8c]] - hMCTSL1 (mutant) + retro-binding inhibitor<br /> | **[[3h89]], [[3h8b]], [[3h8c]] - hMCTSL1 (mutant) + retro-binding inhibitor<br /> | ||
**[[3hwn]], [[3hha]] – hMCTSL1+pyrazole inhibitor<br /> | **[[3hwn]], [[3hha]] – hMCTSL1+pyrazole inhibitor<br /> | ||
| + | **[[5mqy]] – hMCTSL1 + pyrimidine inhibitor<br /> | ||
**[[3kse]] – hMCTSL1 (mutant)+stefin<br /> | **[[3kse]] – hMCTSL1 (mutant)+stefin<br /> | ||
**[[4axm]], [[5mae]], [[5maj]], [[5f02]], [[3bc3]], [[3of9]] – hMCTSL1 catalytic domain + inhibitor<br /> | **[[4axm]], [[5mae]], [[5maj]], [[5f02]], [[3bc3]], [[3of9]] – hMCTSL1 catalytic domain + inhibitor<br /> | ||
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**[[3ovz]] - hMCTSS+ ketoamide inhibitor<br /> | **[[3ovz]] - hMCTSS+ ketoamide inhibitor<br /> | ||
**[[5qc4]] – hMCTSS (mutant)+ thioether acetamide<br /> | **[[5qc4]] – hMCTSS (mutant)+ thioether acetamide<br /> | ||
| - | **[[3iej]] - hMCTSS (mutant)+pyrazole inhibitor<br /> | + | **[[3iej]], [[5qcf]], [[5qce]], [[5qcd]], [[5qcc]], [[5qcg]], [[5qch]], [[5qci]] - hMCTSS (mutant)+pyrazole inhibitor<br /> |
**[[2h7j]], [[2hxz]]- hMCTSS+triazole inhibitor<br /> | **[[2h7j]], [[2hxz]]- hMCTSS+triazole inhibitor<br /> | ||
| - | **[[2r9m]], [[2r9n]], [[2r9o]] – hMCTSS+piperidine inhibitor<br /> | + | **[[2r9m]], [[2r9n]], [[2r9o]], [[5qcj]] – hMCTSS+piperidine inhibitor<br /> |
| + | **[[5qbu]], [[5qbw]], [[5qbx]], [[5qbz]], [[5qc0]], [[5qc1]], [[5qc2]], [[5qc3]], [[5qc5]], [[5qc6]], [[5qc7]], [[5qc8]], [[5qc9]], [[5qca]], [[5qcb]] – hMCTSS (mutant) + piperidine inhibitor<br /> | ||
**[[2op3]], [[2hhn]], [[2g7y]], [[2hh5]], [[2f1g]] – hMCTSS+aryl inhibitor<br /> | **[[2op3]], [[2hhn]], [[2g7y]], [[2hh5]], [[2f1g]] – hMCTSS+aryl inhibitor<br /> | ||
**[[2fud]], [[2fra]], [[2frq]], [[2ft2]], [[1npz]], [[1nqc]], [[4p6e]], [[4p6g]] – hMCTSS+inhibitor<br /> | **[[2fud]], [[2fra]], [[2frq]], [[2ft2]], [[1npz]], [[1nqc]], [[4p6e]], [[4p6g]] – hMCTSS+inhibitor<br /> | ||
Revision as of 09:19, 8 April 2018
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3D Structures of Cathepsin
Updated on 08-April-2018
References
- ↑ Nomura T, Katunuma N. Involvement of cathepsins in the invasion, metastasis and proliferation of cancer cells. J Med Invest. 2005 Feb;52(1-2):1-9. PMID:15751268
- ↑ Mirkovic B, Renko M, Turk S, Sosic I, Jevnikar Z, Obermajer N, Turk D, Gobec S, Kos J. Novel Mechanism of Cathepsin B Inhibition by Antibiotic Nitroxoline and Related Compounds. ChemMedChem. 2011 May 20. doi: 10.1002/cmdc.201100098. PMID:21598397 doi:10.1002/cmdc.201100098
