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Cyclin

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Line 41: Line 41:
**[[2b9r]] – hCYCB1 (mutant)<br />
**[[2b9r]] – hCYCB1 (mutant)<br />
-
**[[2jgz]] - hCYCB1 +CDK2
+
**[[2jgz]] - hCYCB1 + CDK2<br />
 +
**[[5hq0]], [[4yc3]], [[4y72]] – hCYCB1 + hCDK1 + CDK regulatory subunit 2<br />
 +
**[[5lqf]] – hCYCB1 + hCDK1 + CDK regulatory subunit 2 + inhibitor<br />
*CYCC
*CYCC
**[[3rgf]], [[4g6l]] – hCYCC + CDK8<br />
**[[3rgf]], [[4g6l]] – hCYCC + CDK8<br />
-
**[[4f6s]], [[4f6u]], [[4f6w]], [[4f70]], [[4f7j]], [[4f7l]], [[4f7n]], [[4f7s]], [[5idp]], [[5idn]], [[5icp]], [[5i5z]], [[5hvy]], [[5hnb]], [[5hbj]], [[5hbh]], [[5hbe]], [[5fgk]], [[5cei]], [[5bnj]] – hCYCC + CDK8 + inhibitor<br />
+
**[[4f6s]], [[4f6u]], [[4f6w]], [[4f70]], [[4f7j]], [[4f7l]], [[4f7n]], [[4f7s]], [[5idp]], [[5idn]], [[5icp]], [[5i5z]], [[5hvy]], [[5hnb]], [[5hbj]], [[5hbh]], [[5hbe]], [[5fgk]], [[5cei]], [[5bnj]], [[5xqx]], [[5xs2]] – hCYCC + CDK8 + inhibitor<br />
*CYCD
*CYCD
**[[2w96]], [[2w99]], [[2w9f]], [[2w9z]] - hCYCD1 +CDK4 (mutant)<br />
**[[2w96]], [[2w99]], [[2w9f]], [[2w9z]] - hCYCD1 +CDK4 (mutant)<br />
-
**[[3g33]] – hCYCD3 +CDK4
+
**[[6ei2]] – hCYCD2 + HLA + microglobulin<br />
 +
**[[3g33]] – hCYCD3 + CDK4
*CYCE
*CYCE
-
**[[1w98]] – hCYCE1 +CDK2 T160P<br />
+
**[[1w98]] – hCYCE1 + CDK2 T160P<br />
**[[5l2w]] – hCYCE1 + CDK2 + drug<br />
**[[5l2w]] – hCYCE1 + CDK2 + drug<br />
Line 68: Line 71:
**[[4cxa]] - hCYCK + CDK12 T160P + AMPPNP<br />
**[[4cxa]] - hCYCK + CDK12 T160P + AMPPNP<br />
**[[5efq]], [[4nst]] - hCYCK + CDK13 T160P + ADP<br />
**[[5efq]], [[4nst]] - hCYCK + CDK13 T160P + ADP<br />
-
**[[4un0]], [[5acb]] - hCYCK +CDK12 T160P+inhibitor<br />
+
**[[4un0]], [[5acb]], [[6b3e]] - hCYCK +CDK12 T160P + inhibitor<br />
*CYCT
*CYCT

Revision as of 09:06, 17 April 2018

Cyclin T1 (green) complex with CDK9 (cyan) and TRIS (PDB entry 3blh)

Drag the structure with the mouse to rotate

3D Structures of Cyclin

Updated on 17-April-2018

References

  1. Galderisi U, Jori FP, Giordano A. Cell cycle regulation and neural differentiation. Oncogene. 2003 Aug 11;22(33):5208-19. PMID:12910258 doi:http://dx.doi.org/10.1038/sj.onc.1206558
  2. Noble ME, Endicott JA, Brown NR, Johnson LN. The cyclin box fold: protein recognition in cell-cycle and transcription control. Trends Biochem Sci. 1997 Dec;22(12):482-7. PMID:9433129

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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