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14-3-3 protein

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Line 27: Line 27:
*14-3-3 protein σ binary complex with peptide
*14-3-3 protein σ binary complex with peptide
-
**[[1ywt]] – hPRS + phosphopeptide <br />
+
**[[1ywt]], [[5mhc]] – hPRS + phosphopeptide <br />
-
**[[3lw1]] – hPRS + p53 peptide <br />
+
**[[3lw1]], [[5moc]], [[5mxo]] – hPRS + p53 peptide <br />
**[[3iqj]], [[3iqu]], [[4iea]] – hPRS + Raf-1 peptide <br />
**[[3iqj]], [[3iqu]], [[4iea]] – hPRS + Raf-1 peptide <br />
**[[3mhr]] – hPRS + YAP peptide <br />
**[[3mhr]] – hPRS + YAP peptide <br />
Line 39: Line 39:
**[[5lu1]], [[5lu2]] – hPRS (mutant) + HSPB6 peptide<br />
**[[5lu1]], [[5lu2]] – hPRS (mutant) + HSPB6 peptide<br />
**[[4qli]] – hPRS + SNAI1 peptide <br />
**[[4qli]] – hPRS + SNAI1 peptide <br />
 +
**[[5my9]], [[5myc]] – hPRS + LRRK2 peptide <br />
 +
**[[5n5r]], [[5n5t]], [[5n5w]], [[5n75]] – hPRS + taz ps89 peptide <br />
 +
**[[5ok9]], [[5okf]] – hPRS/HSPB6 <br />
 +
**[[5om0]] – hPRS/GLI1 <br />
 +
**[[5oma]] – hPRS/STRAD1 + peptide <br />
*14-3-3 protein σ binary complex with small molecule
*14-3-3 protein σ binary complex with small molecule
Line 64: Line 69:
**[[3rdh]] – hPRS <br />
**[[3rdh]] – hPRS <br />
**[[3rdh]] – hPRS/LKB1 <br />
**[[3rdh]] – hPRS/LKB1 <br />
-
**[[1qjb]] – hPRS + phosphopeptide <br />
+
**[[1qjb]], [[1qja]], [[6eww]] – hPRS + phosphopeptide <br />
**[[2c1j]], [[2c1n]] – hPRS + histone H3 peptide <br />
**[[2c1j]], [[2c1n]] – hPRS + histone H3 peptide <br />
**[[2o02]], [[4n7g]], [[4n7y]], [[4n84]], [[5j31]] – hPRS + exoenzyme S peptide <br />
**[[2o02]], [[4n7g]], [[4n7y]], [[4n84]], [[5j31]] – hPRS + exoenzyme S peptide <br />
**[[2v7d]], [[4hkc]] – hPRS + integrin peptide <br />
**[[2v7d]], [[4hkc]] – hPRS + integrin peptide <br />
 +
**[[5jm4]] – hPRS + peptide <br />
 +
**[[5nas]] – hPRS + PI4KIIIB peptide <br />
 +
**[[5m35]], [[5m36]], [[5m37]] – hPRS + M-phase phosphatase peptide <br />
 +
**[[5ulo]] – hPRS + TBC1D7 peptide <br />
 +
**[[6ejl]] – hPRS + MAP3K 5 peptide <br />
 +
**[[6f08]] – hPRS + SOS-1 peptide <br />
**[[3cu8]], [[3nkx]], [[4fj3]], [[4ihl]] – hPRS + Raf-1 peptide <br />
**[[3cu8]], [[3nkx]], [[4fj3]], [[4ihl]] – hPRS + Raf-1 peptide <br />
**[[2wh0]] – hPRS + protein kinase C ε peptide <br />
**[[2wh0]] – hPRS + protein kinase C ε peptide <br />
Line 84: Line 95:
**[[4o46]] – hPRS + influenza C-terminal peptide <br />
**[[4o46]] – hPRS + influenza C-terminal peptide <br />
**[[5d3e]] – hPRS + CFTR peptide <br />
**[[5d3e]] – hPRS + CFTR peptide <br />
 +
**[[6fel]] – hPRS + CAMKK 2 peptide <br />
*14-3-3 protein β/α
*14-3-3 protein β/α
Line 89: Line 101:
**[[2bq0]], [[4dnk]] – hPRS <br />
**[[2bq0]], [[4dnk]] – hPRS <br />
**[[2c23]] – hPRS + exoenzyme S peptide <br />
**[[2c23]] – hPRS + exoenzyme S peptide <br />
-
**[[4gnt]] – PRS + CHREBP peptide - mouse<br />
+
**[[5n10]] – hPRS + estrogen receptor peptide <br />
 +
**[[4gnt]] – mPRS + CHREBP peptide - mouse<br />
 +
**[[5f74]] – mPRS + CHREBP + AMP<br />
*14-3-3 protein θ
*14-3-3 protein θ
Line 99: Line 113:
**[[2c63]], [[2c74]] – hPRS + phosphopeptide <br />
**[[2c63]], [[2c74]] – hPRS + phosphopeptide <br />
 +
**[[5yqg]] – hPRS + NUMB peptide <br />
*14-3-3 protein ε
*14-3-3 protein ε
-
**[[2br9]] – hPRS + phosphopeptide <br />
+
**[[2br9]], [[6eih]] – hPRS + phosphopeptide <br />
**[[3ual]], [[3ubw]] – hPRS + myeloid leukemia factor 1 peptide <br />
**[[3ual]], [[3ubw]] – hPRS + myeloid leukemia factor 1 peptide <br />
Line 109: Line 124:
**[[3efz]] – PRS + phosphoserine – ''Cryptosporidium parvum''<br />
**[[3efz]] – PRS + phosphoserine – ''Cryptosporidium parvum''<br />
**[[4f7r]] – PRS – ''Giardia intestinalis''<br />
**[[4f7r]] – PRS – ''Giardia intestinalis''<br />
 +
 +
*14-3-3-like protein C
 +
 +
**[[1o9c]], [[1o9e]] – tPRS - tobacco<br />
 +
**[[1o9d]], [[1o9f]], [[2o98]], [[3e6y]] – tPRS + H+ ATPase peptide<br />
 +
**[[5nwi]], [[5nwj]], [[5nwk]] – tPRS + potassium channel peptide <br />
 +
**[[3m50]], [[3m51]] – tPRS + PMA2 peptide + stabilizer<br />
 +
 +
*14-3-3-like protein GF14-C
 +
 +
**[[3axy]] – PRS + HD3A + OSFD1 - rice<br />
 +
 +
*14-3-3-like protein E
 +
 +
**[[4dx0]] – tPRS + PMA2 peptide + stabilizer<br />
 +
}}
}}

Revision as of 07:55, 1 March 2018

Structure of human 14-3-3 protein ζ with phosphopeptide (yellow) (PDB code 1qja).

Drag the structure with the mouse to rotate

3D structures of 14-3-3 proteins (Updated on 01-March-2018)

References

  1. ↑ Benzinger A, Popowicz GM, Joy JK, Majumdar S, Holak TA, Hermeking H. The crystal structure of the non-liganded 14-3-3sigma protein: insights into determinants of isoform specific ligand binding and dimerization. Cell Res. 2005 Apr;15(4):219-27. PMID:15857576 doi:10.1038/sj.cr.7290290

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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