A-kinase anchor protein

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 23: Line 23:
*A-kinase anchor protein 10
*A-kinase anchor protein 10
-
**[[3tmh]] – hAKAP10 A-kinase-binding domain + cAMP-dependent protein kinase type II-alpha regulatory subunit + NHERF-3 <br />
+
**[[3tmh]] – hAKAP10 A-kinase-binding domain + cAMP-dependent protein kinase type II-α regulatory subunit + NHERF-3 <br />
*A-kinase anchor protein 13
*A-kinase anchor protein 13
Line 36: Line 36:
**[[5jj2]] – hAKAP18 2H phosphoestease domain <br />
**[[5jj2]] – hAKAP18 2H phosphoestease domain <br />
**[[2vfl]] – hAKAP18 2H phosphoestease domain + CMP<br />
**[[2vfl]] – hAKAP18 2H phosphoestease domain + CMP<br />
-
**[[3j4q]], [[3j4r]] – hAKAP18 residues 1-353 + cAMP-dependent protein kinase type II-alpha regulatory subunit + PKA C-alpha – Cryo EM <br />
+
**[[3j4q]], [[3j4r]] – hAKAP18 residues 1-353 + cAMP-dependent protein kinase type II-α regulatory subunit + PKA C-alpha – Cryo EM <br />
-
**[[4zp3]] – hAKAP18 residues 43-82 + cAMP-dependent protein kinase type II-alpha regulatory subunit <br />
+
**[[4zp3]] – hAKAP18 residues 43-82 + cAMP-dependent protein kinase type II-α regulatory subunit <br />
*Small membrane A-kinase anchor protein
*Small membrane A-kinase anchor protein
-
**[[5hvz]] – hsmAKAP A-kinase-binding domain + cAMP-dependent protein kinase type II-alpha regulatory subunit <br />
+
**[[5hvz]] – hsmAKAP A-kinase-binding domain + cAMP-dependent protein kinase type II-α regulatory subunit <br />
}}
}}
== References ==
== References ==

Revision as of 11:58, 31 December 2017

Human AKAP18 helix (olive) complex with a dimer of cAMP-dependent protein kinase regulatory subunit (grey and green) and Cd+2 ions (PDB code 4zp3)

Drag the structure with the mouse to rotate

3D Structures of A-kinase anchor protein

Updated on 31-December-2017

References

  1. Edwards AS, Scott JD. A-kinase anchoring proteins: protein kinase A and beyond. Curr Opin Cell Biol. 2000 Apr;12(2):217-21. PMID:10712918
  2. Carr DW, Newell AE. The role of A-kinase anchoring proteins (AKaps) in regulating sperm function. Soc Reprod Fertil Suppl. 2007;63:135-41. PMID:17566268
  3. Diviani D, Dodge-Kafka KL, Li J, Kapiloff MS. A-kinase anchoring proteins: scaffolding proteins in the heart. Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1742-53. doi:, 10.1152/ajpheart.00569.2011. Epub 2011 Aug 19. PMID:21856912 doi:http://dx.doi.org/10.1152/ajpheart.00569.2011
  4. Gotz F, Roske Y, Schulz MS, Autenrieth K, Bertinetti D, Faelber K, Zuhlke K, Kreuchwig A, Kennedy E, Krause G, Daumke O, Herberg FW, Heinemann U, Klussmann E. AKAP18:PKA-RIIalpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA. Biochem J. 2016 Apr 21. pii: BCJ20160242. PMID:27102985 doi:http://dx.doi.org/10.1042/BCJ20160242

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Personal tools