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5wfw
From Proteopedia
(Difference between revisions)
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==Crystal structure of the influenza virus PA endonuclease (E119D mutant) in complex with inhibitor 10j (SRI-30026)== | ==Crystal structure of the influenza virus PA endonuclease (E119D mutant) in complex with inhibitor 10j (SRI-30026)== | ||
| - | <StructureSection load='5wfw' size='340' side='right' caption='[[5wfw]], [[Resolution|resolution]] 2.29Å' scene=''> | + | <StructureSection load='5wfw' size='340' side='right'caption='[[5wfw]], [[Resolution|resolution]] 2.29Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5wfw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WFW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WFW FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5wfw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/I09a0 I09a0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WFW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WFW FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GYA:2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-N-(5,6-dimethoxy-2,3-dihydro-1H-inden-2-yl)-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide'>GYA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GYA:2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-N-(5,6-dimethoxy-2,3-dihydro-1H-inden-2-yl)-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide'>GYA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5w3i|5w3i]], [[5w44|5w44]], [[5wef|5wef]], [[5wei|5wei]], [[5we9|5we9]], [[5w73|5w73]], [[5w7u|5w7u]], [[5w92|5w92]], [[5w9g|5w9g]], [[5wf3|5wf3]], [[5wa6|5wa6]], [[5wa7|5wa7]], [[5web|5web]], [[5wfm|5wfm]], [[5wap|5wap]], [[5wb3|5wb3]], [[5wdw|5wdw]], [[5wcs|5wcs]], [[5wct|5wct]], [[5wdn|5wdn]], [[5we7|5we7]], [[5wdc|5wdc]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5w3i|5w3i]], [[5w44|5w44]], [[5wef|5wef]], [[5wei|5wei]], [[5we9|5we9]], [[5w73|5w73]], [[5w7u|5w7u]], [[5w92|5w92]], [[5w9g|5w9g]], [[5wf3|5wf3]], [[5wa6|5wa6]], [[5wa7|5wa7]], [[5web|5web]], [[5wfm|5wfm]], [[5wap|5wap]], [[5wb3|5wb3]], [[5wdw|5wdw]], [[5wcs|5wcs]], [[5wct|5wct]], [[5wdn|5wdn]], [[5we7|5we7]], [[5wdc|5wdc]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=641501 I09A0])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wfw OCA], [http://pdbe.org/5wfw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wfw RCSB], [http://www.ebi.ac.uk/pdbsum/5wfw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wfw ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wfw OCA], [http://pdbe.org/5wfw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wfw RCSB], [http://www.ebi.ac.uk/pdbsum/5wfw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wfw ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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</div> | </div> | ||
<div class="pdbe-citations 5wfw" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5wfw" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[RNA polymerase|RNA polymerase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: I09a0]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Kumar, G]] | [[Category: Kumar, G]] | ||
[[Category: White, S W]] | [[Category: White, S W]] | ||
Revision as of 17:35, 11 December 2019
Crystal structure of the influenza virus PA endonuclease (E119D mutant) in complex with inhibitor 10j (SRI-30026)
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