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Dehalogenase

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Line 87: Line 87:
**[[1y37]] – BuFDH – ''Burkholderia''<br />
**[[1y37]] – BuFDH – ''Burkholderia''<br />
-
**[[3r3u]] – RpFDH – ''Rhodopseudomonas palustris''<br />
+
**[[3r3u]], [[5nyv]], [[5k3d]], [[5k3c]] – RpFDH – ''Rhodopseudomonas palustris''<br />
-
**[[3r40]], [[3r41]], [[5t4t]] – RpFDH (mutant) <br />
+
**[[3r40]], [[3r41]], [[5t4t]], [[5k3f]], [[5k3e]] – RpFDH (mutant) <br />
*''Fluoroacetate dehalogenase complexes''
*''Fluoroacetate dehalogenase complexes''
-
**[[3r3v]], [[3r3y]], [[5swn]] – RpFDH (mutant) + fluoroacetate<br />
+
**[[3r3v]], [[3r3y]], [[5swn]], [[5k3a]] – RpFDH (mutant) + fluoroacetate<br />
-
**[[3r3w]] – RpFDH (mutant) + chloroacetate<br />
+
**[[5k3c]] – RpFDH + fluorotryptophan<br />
 +
**[[3r3w]], [[5k3b]] – RpFDH (mutant) + chloroacetate<br />
**[[3r3x]] – RpFDH (mutant) + bromoacetate<br />
**[[3r3x]] – RpFDH (mutant) + bromoacetate<br />
**[[3r3z]] – RpFDH + glycolate<br />
**[[3r3z]] – RpFDH + glycolate<br />
Line 121: Line 122:
**[[2yml]], [[2ymm]], [[2ymp]], [[2ymq]] – RhLHDH <br />
**[[2yml]], [[2ymm]], [[2ymp]], [[2ymq]] – RhLHDH <br />
**[[4ce6]], [[4cf3]], [[4cf4]], [[4cf5]], [[4cnq]] – RhLHDH (mutant)<br />
**[[4ce6]], [[4cf3]], [[4cf4]], [[4cf5]], [[4cnq]] – RhLHDH (mutant)<br />
-
**[[3bjx]] – LHDH – ''Pseudomonas putida'' <br />
+
**[[3bjx]] – PpLHDH – ''Pseudomonas putida'' <br />
**[[3umc]] – LHDH – ''Pseudomonas aeruginosa'' <br />
**[[3umc]] – LHDH – ''Pseudomonas aeruginosa'' <br />
**[[3um9]] – LHDH – ''Polaromonas'' <br />
**[[3um9]] – LHDH – ''Polaromonas'' <br />
Line 135: Line 136:
**[[1qq6]], [[1qq7]] – XaLHDH + aspartate carboxymethyl ester + Cl<br />
**[[1qq6]], [[1qq7]] – XaLHDH + aspartate carboxymethyl ester + Cl<br />
**[[2yn4]] – RhLHDH + chlorobutyrate<br />
**[[2yn4]] – RhLHDH + chlorobutyrate<br />
 +
 +
*R-2-haloacid dehalogenase (RHDH)
 +
 +
**[[5h00]], [[5gzy]] – PpRHDH <br />
 +
**[[5h01]] – PpRHDH (mutant) <br />
 +
**[[5gzx]] – PpRHDH (mutant) + chloropropionate<br />
*DL-2-haloacid dehalogenase (DLHDH)
*DL-2-haloacid dehalogenase (DLHDH)
Line 183: Line 190:
**[[4ur0]] – SmTCRD catalytic subunit + trichloroethene<br />
**[[4ur0]] – SmTCRD catalytic subunit + trichloroethene<br />
**[[4ur1]] – SmTCRD catalytic subunit + tribromoethene<br />
**[[4ur1]] – SmTCRD catalytic subunit + tribromoethene<br />
 +
**[[5m2g]], [[5m8u]], [[5m91]], [[5m92]], [[5maa]] – SmTCRD catalytic subunit + bromophenol derivative<br />
 +
**[[5m8w]], [[5m8x]], [[5m8y]], [[5ma0]], [[5ma1]] – SmTCRD catalytic subunit + chlorophenol derivative<br />
 +
**[[5m8z]], [[5m90]] – SmTCRD catalytic subunit + fluoroophenol derivative<br />
 +
**[[5ma2]] – SmTCRD catalytic subunit + iodophenol<br />
 +
**[[5obi]], [[5obp]] – SmTCRD catalytic subunit + cofactor<br />
**[[4ur2]] – SmTCRD catalytic subunit + iodide<br />
**[[4ur2]] – SmTCRD catalytic subunit + iodide<br />

Revision as of 09:05, 24 April 2018

Structure of haloalkane dehalogenase complex with I- ion (purple) (PDB code 2edc).

Drag the structure with the mouse to rotate

3D structures of dehalogenase

Updated on 24-April-2018


References

  1. ↑ Koudelakova T, Chovancova E, Brezovsky J, Monincova M, Fortova A, Jarkovsky J, Damborsky J. Substrate specificity of haloalkane dehalogenases. Biochem J. 2011 Apr 15;435(2):345-54. doi: 10.1042/BJ20101405. PMID:21294712 doi:http://dx.doi.org/10.1042/BJ20101405
  2. ↑ Verschueren KH, Kingma J, Rozeboom HJ, Kalk KH, Janssen DB, Dijkstra BW. Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site. Biochemistry. 1993 Sep 7;32(35):9031-7. PMID:8369276

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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