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5msa

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==Crystal structure of human carbonic anhydrase isozyme XII with 2,3,5,6-Tetrafluoro-4-(propylthio)benzenesulfonamide==
==Crystal structure of human carbonic anhydrase isozyme XII with 2,3,5,6-Tetrafluoro-4-(propylthio)benzenesulfonamide==
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<StructureSection load='5msa' size='340' side='right' caption='[[5msa]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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<StructureSection load='5msa' size='340' side='right'caption='[[5msa]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5msa]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MSA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MSA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5msa]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MSA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MSA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3TV:2,3,5,6-TETRAFLUORO-4-(PROPYLSULFANYL)BENZENESULFONAMIDE'>3TV</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3TV:2,3,5,6-TETRAFLUORO-4-(PROPYLSULFANYL)BENZENESULFONAMIDE'>3TV</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5llc|5llc]], [[5lle|5lle]], [[5llg|5llg]], [[5llh|5llh]], [[5lln|5lln]], [[5llo|5llo]], [[5llp|5llp]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5llc|5llc]], [[5lle|5lle]], [[5llg|5llg]], [[5llh|5llh]], [[5lln|5lln]], [[5llo|5llo]], [[5llp|5llp]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5msa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5msa OCA], [http://pdbe.org/5msa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5msa RCSB], [http://www.ebi.ac.uk/pdbsum/5msa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5msa ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5msa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5msa OCA], [http://pdbe.org/5msa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5msa RCSB], [http://www.ebi.ac.uk/pdbsum/5msa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5msa ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CAH12_HUMAN CAH12_HUMAN]] Reversible hydration of carbon dioxide.
[[http://www.uniprot.org/uniprot/CAH12_HUMAN CAH12_HUMAN]] Reversible hydration of carbon dioxide.
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==See Also==
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*[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
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[[Category: Large Structures]]
[[Category: Grazulis, S]]
[[Category: Grazulis, S]]
[[Category: Manakova, E]]
[[Category: Manakova, E]]

Revision as of 07:27, 19 August 2020

Crystal structure of human carbonic anhydrase isozyme XII with 2,3,5,6-Tetrafluoro-4-(propylthio)benzenesulfonamide

PDB ID 5msa

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