1obv
From Proteopedia
(New page: 200px<br /> <applet load="1obv" size="450" color="white" frame="true" align="right" spinBox="true" caption="1obv, resolution 2.10Å" /> '''Y94F FLAVODOXIN FRO...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1OBV is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Anabaena_sp. Anabaena sp.]] with SO4 and FMN as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1OBV OCA]]. | + | 1OBV is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Anabaena_sp. Anabaena sp.]] with SO4 and FMN as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: FMN. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1OBV OCA]]. |
==Reference== | ==Reference== | ||
| Line 25: | Line 25: | ||
[[Category: flavoprotein]] | [[Category: flavoprotein]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:11:54 2007'' |
Revision as of 09:07, 30 October 2007
|
Y94F FLAVODOXIN FROM ANABAENA
Overview
Molecular recognition begins when two molecules approach and establish, interactions of certain strength. The mechanisms of molecular recognition, reactions between biological molecules are not well known, and few systems, have been analyzed in detail. We investigate here the reaction between an, apoprotein and its physiological cofactor (apoflavodoxin and flavin, mononucleotide) that binds reversibly to form a non-covalent complex, (flavodoxin) involved in electron transfer reactions. We have analyzed the, fast binding reactions between the FMN cofactor (and shorter analogs) and, wild type (and nine mutant apoflavodoxins where residues interacting with, FMN in the final complex have been replaced). The x-ray structures of two, such mutants are reported that show the mutations are well ... [(full description)]
About this Structure
1OBV is a [Single protein] structure of sequence from [Anabaena sp.] with SO4 and FMN as [ligands]. Structure known Active Site: FMN. Full crystallographic information is available from [OCA].
Reference
How FMN binds to anabaena apoflavodoxin: a hydrophobic encounter at an open binding site., Lostao A, Daoudi F, Irun MP, Ramon A, Fernandez-Cabrera C, Romero A, Sancho J, J Biol Chem. 2003 Jun 27;278(26):24053-61. Epub 2003 Apr 7. PMID:12682068
Page seeded by OCA on Tue Oct 30 11:11:54 2007
