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5v54
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of 5-HT1B receptor in complex with methiothepin== | |
| - | + | <StructureSection load='5v54' size='340' side='right' caption='[[5v54]], [[Resolution|resolution]] 3.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5v54]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V54 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V54 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=89F:1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine'>89F</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v54 OCA], [http://pdbe.org/5v54 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v54 RCSB], [http://www.ebi.ac.uk/pdbsum/5v54 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v54 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/5HT1B_HUMAN 5HT1B_HUMAN]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Caffrey, M]] | [[Category: Caffrey, M]] | ||
| - | [[Category: | + | [[Category: Cai, X]] |
| - | + | ||
[[Category: Dai, A]] | [[Category: Dai, A]] | ||
| - | + | [[Category: Huang, C Y]] | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | [[Category: Huang, C | + | |
| - | + | ||
| - | + | ||
[[Category: Jiang, Y]] | [[Category: Jiang, Y]] | ||
[[Category: Liu, B]] | [[Category: Liu, B]] | ||
[[Category: Liu, P]] | [[Category: Liu, P]] | ||
| + | [[Category: Melcher, K]] | ||
| + | [[Category: Waal, P de]] | ||
| + | [[Category: Wang, M T]] | ||
| + | [[Category: Wang, M W]] | ||
| + | [[Category: Xu, H E]] | ||
[[Category: Xu, Y]] | [[Category: Xu, Y]] | ||
| - | [[Category: | + | [[Category: Yang, D]] |
| - | [[Category: | + | [[Category: Yin, W C]] |
| + | [[Category: Yin, Y]] | ||
| + | [[Category: Zhou, X E]] | ||
| + | [[Category: 5-hydroxytryptamine]] | ||
| + | [[Category: Electron transport]] | ||
| + | [[Category: Gpcr antagonist]] | ||
| + | [[Category: Ob1]] | ||
Revision as of 06:13, 7 February 2018
Crystal structure of 5-HT1B receptor in complex with methiothepin
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Categories: Caffrey, M | Cai, X | Dai, A | Huang, C Y | Jiang, Y | Liu, B | Liu, P | Melcher, K | Waal, P de | Wang, M T | Wang, M W | Xu, H E | Xu, Y | Yang, D | Yin, W C | Yin, Y | Zhou, X E | 5-hydroxytryptamine | Electron transport | Gpcr antagonist | Ob1
