6fii
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Tubulin-Spongistatin complex== | |
| - | + | <StructureSection load='6fii' size='340' side='right' caption='[[6fii]], [[Resolution|resolution]] 2.41Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6fii]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FII OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FII FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SG9:Spongistatin-1'>SG9</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fii OCA], [http://pdbe.org/6fii PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fii RCSB], [http://www.ebi.ac.uk/pdbsum/6fii PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fii ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref> [[http://www.uniprot.org/uniprot/TBB2B_BOVIN TBB2B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Altmann, K H]] | ||
| + | [[Category: Angell, D Lucena]] | ||
| + | [[Category: Bucher, P]] | ||
| + | [[Category: Diaz, J F]] | ||
| + | [[Category: Menchon, G]] | ||
| + | [[Category: Mueller, R]] | ||
| + | [[Category: Paterson, I]] | ||
| + | [[Category: Prota, A E]] | ||
| + | [[Category: Steinmetz, M O]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Cytoskeleton]] | ||
| + | [[Category: Microtubule]] | ||
| + | [[Category: Tubulin fold]] | ||
Revision as of 05:39, 30 May 2018
Tubulin-Spongistatin complex
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