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2k2q
From Proteopedia
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==complex structure of the external thioesterase of the Surfactin-synthetase with a carrier domain== | ==complex structure of the external thioesterase of the Surfactin-synthetase with a carrier domain== | ||
| - | <StructureSection load='2k2q' size='340' side='right' caption='[[2k2q]], [[NMR_Ensembles_of_Models | 18 NMR models]]' scene=''> | + | <StructureSection load='2k2q' size='340' side='right'caption='[[2k2q]], [[NMR_Ensembles_of_Models | 18 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2k2q]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2k2q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [https://en.wikipedia.org/wiki/Brevibacillus_parabrevis Brevibacillus parabrevis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K2Q FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ron|2ron]], [[2gdx|2gdx]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ron|2ron]], [[2gdx|2gdx]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tycC ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tycC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=54914 Brevibacillus parabrevis]), srfAD, srfA4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k2q OCA], [https://pdbe.org/2k2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k2q RCSB], [https://www.ebi.ac.uk/pdbsum/2k2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k2q ProSAT]</span></td></tr> |
</table> | </table> | ||
| - | {{Large structure}} | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/TYCC_BREPA TYCC_BREPA]] Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product. [[https://www.uniprot.org/uniprot/SRFAD_BACSU SRFAD_BACSU]] Probable thioesterase involved in the biosynthesis of surfactin. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: Brevibacillus parabrevis]] | [[Category: Brevibacillus parabrevis]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Bernhard, F]] | [[Category: Bernhard, F]] | ||
[[Category: Dotsch, V]] | [[Category: Dotsch, V]] | ||
Revision as of 08:06, 7 April 2021
complex structure of the external thioesterase of the Surfactin-synthetase with a carrier domain
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Categories: Bacillus subtilis | Brevibacillus parabrevis | Large Structures | Bernhard, F | Dotsch, V | Frueh, D P | Guntert, P | Koglin, A | Lohr, F | Marahiel, M A | Mofid, M R | Rogov, V V | Strieter, E R | Wagner, G | Walsh, C T | A/b-hydrolase | Antibiotic biosynthesis | Ligase | Ligase-hydrolase complex | Multifunctional enzyme | Non-ribosomal peptide synthetase | Nrp | Phosphopantetheine | Sporulation | Stress response | Thioesterase | Type ii thioesterase

