2p57
From Proteopedia
(Difference between revisions)
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==GAP domain of ZNF289, an ID1-regulated zinc finger protein== | ==GAP domain of ZNF289, an ID1-regulated zinc finger protein== | ||
| - | <StructureSection load='2p57' size='340' side='right' caption='[[2p57]], [[Resolution|resolution]] 1.80Å' scene=''> | + | <StructureSection load='2p57' size='340' side='right'caption='[[2p57]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2p57]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2p57]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P57 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P57 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZNF289 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZNF289 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p57 OCA], [https://pdbe.org/2p57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p57 RCSB], [https://www.ebi.ac.uk/pdbsum/2p57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p57 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ARFG2_HUMAN ARFG2_HUMAN]] GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.<ref>PMID:17760859</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Bochkarev, A]] | [[Category: Bochkarev, A]] | ||
Revision as of 15:16, 17 June 2021
GAP domain of ZNF289, an ID1-regulated zinc finger protein
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Categories: Human | Large Structures | Arrowsmith, C H | Bochkarev, A | Dimov, S | Edwards, A M | Landry, R | Park, H | Structural genomic | Shen, L | Sundstrom, M | Tempel, W | Tong, Y | Weigelt, J | Zhu, H | Gap | Gtpase activating protein | Metal binding protein | Sgc | Zinc finger
