2px7
From Proteopedia
(Difference between revisions)
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==Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8== | ==Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8== | ||
| - | <StructureSection load='2px7' size='340' side='right' caption='[[2px7]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='2px7' size='340' side='right'caption='[[2px7]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2px7]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2px7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PX7 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ispD, TTHA0171 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ispD, TTHA0171 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_4-phosphate_cytidylyltransferase 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.60 2.7.7.60] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2px7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2px7 OCA], [https://pdbe.org/2px7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2px7 RCSB], [https://www.ebi.ac.uk/pdbsum/2px7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2px7 ProSAT], [https://www.topsan.org/Proteins/RSGI/2px7 TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ISPD_THET8 ISPD_THET8]] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2px7 ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2px7 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[MEP cytidylyltransferase 3D structures|MEP cytidylyltransferase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]] | [[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Thet8]] | [[Category: Thet8]] | ||
[[Category: Chang, S H]] | [[Category: Chang, S H]] | ||
Revision as of 15:35, 17 June 2021
Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8
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Categories: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase | Large Structures | Thet8 | Chang, S H | Chen, L | Chen, L Q | Ebihara, A | Kuramitsu, S | Lee, D | Liu, Z J | Nguyen, D | Structural genomic | Rose, J P | Shinkai, A | Tsukuda, M | Wang, B C | Yokoyama, S | 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase | Ispd | Ispd thet8 | National project on protein structural and functional analyse | Nppsfa | PSI, Protein structure initiative | Rsgi | Secsg | Transferase | Ttha0171
