3zon
From Proteopedia
(Difference between revisions)
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==Human TYK2 pseudokinase domain bound to a kinase inhibitor== | ==Human TYK2 pseudokinase domain bound to a kinase inhibitor== | ||
| - | <StructureSection load='3zon' size='340' side='right' caption='[[3zon]], [[Resolution|resolution]] 2.15Å' scene=''> | + | <StructureSection load='3zon' size='340' side='right'caption='[[3zon]], [[Resolution|resolution]] 2.15Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3zon]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZON OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZON FirstGlance]. <br> | <table><tr><td colspan='2'>[[3zon]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZON OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZON FirstGlance]. <br> | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/TYK2_HUMAN TYK2_HUMAN]] Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.<ref>PMID:7526154</ref> | [[http://www.uniprot.org/uniprot/TYK2_HUMAN TYK2_HUMAN]] Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.<ref>PMID:7526154</ref> | ||
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| + | ==See Also== | ||
| + | *[[Tyrosine kinase 3D structures|Tyrosine kinase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Berridge, G]] | [[Category: Berridge, G]] | ||
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
Revision as of 13:28, 1 January 2020
Human TYK2 pseudokinase domain bound to a kinase inhibitor
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Categories: Human | Large Structures | Berridge, G | Bountra, C | Chalk, R | Daga, N | Delft, F von | Edwards, A | Elkins, J M | Knapp, S | Krojer, T | Picaud, S | Salah, E | Savitsky, P | Wang, J | Jak | Transferase
