4egr

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==2.50 angstrom resolution structure of 3-phosphoshikimate 1-carboxyvinyltransferase (AroA) from Coxiella burnetii in complex with phosphoenolpyruvate==
==2.50 angstrom resolution structure of 3-phosphoshikimate 1-carboxyvinyltransferase (AroA) from Coxiella burnetii in complex with phosphoenolpyruvate==
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<StructureSection load='4egr' size='340' side='right' caption='[[4egr]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='4egr' size='340' side='right'caption='[[4egr]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4egr]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"rickettsia_burneti"_(sic)_derrick_1939 "rickettsia burneti" (sic) derrick 1939]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EGR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EGR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4egr]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxiella_burnetii Coxiella burnetii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EGR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EGR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3slh|3slh]], [[3roi|3roi]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4egr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4egr OCA], [https://pdbe.org/4egr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4egr RCSB], [https://www.ebi.ac.uk/pdbsum/4egr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4egr ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aroA, CBU_0526 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=777 "Rickettsia burneti" (sic) Derrick 1939])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-phosphoshikimate_1-carboxyvinyltransferase 3-phosphoshikimate 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.19 2.5.1.19] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4egr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4egr OCA], [http://pdbe.org/4egr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4egr RCSB], [http://www.ebi.ac.uk/pdbsum/4egr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4egr ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AROA_COXBU AROA_COXBU]] Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.[HAMAP-Rule:MF_00210]
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[[https://www.uniprot.org/uniprot/AROA_COXBU AROA_COXBU]] Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.[HAMAP-Rule:MF_00210]
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==See Also==
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*[[EPSP synthase|EPSP synthase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3-phosphoshikimate 1-carboxyvinyltransferase]]
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[[Category: Coxiella burnetii]]
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[[Category: Anderson, W F]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Anderson WF]]
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[[Category: Krishna, S N]]
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[[Category: Krishna SN]]
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[[Category: Kwon, K]]
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[[Category: Kwon K]]
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[[Category: Light, S H]]
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[[Category: Light SH]]
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[[Category: Minasov, G]]
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[[Category: Minasov G]]
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[[Category: Shuvalova, L]]
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[[Category: Shuvalova L]]
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[[Category: 3-phosphoshikimate 1- carboxyvinyl transferase activity]]
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[[Category: Csgid]]
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[[Category: National institute of allergy and infectious disease]]
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[[Category: Niaid]]
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[[Category: Transferase]]
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Revision as of 07:10, 28 September 2022

2.50 angstrom resolution structure of 3-phosphoshikimate 1-carboxyvinyltransferase (AroA) from Coxiella burnetii in complex with phosphoenolpyruvate

PDB ID 4egr

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