4j39

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==Crystal structure of p19 in complex with double-helical 19mer RNA p(CAG)3C(CUG)3==
==Crystal structure of p19 in complex with double-helical 19mer RNA p(CAG)3C(CUG)3==
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<StructureSection load='4j39' size='340' side='right' caption='[[4j39]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='4j39' size='340' side='right'caption='[[4j39]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4j39]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Tbsv Tbsv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J39 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J39 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4j39]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Tomato_bushy_stunt_virus Tomato bushy stunt virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J39 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J39 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4e5c|4e5c]], [[4e6b|4e6b]], [[4e48|4e48]], [[1r9f|1r9f]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j39 OCA], [https://pdbe.org/4j39 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j39 RCSB], [https://www.ebi.ac.uk/pdbsum/4j39 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j39 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ORF4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12145 TBSV])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j39 OCA], [http://pdbe.org/4j39 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4j39 RCSB], [http://www.ebi.ac.uk/pdbsum/4j39 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4j39 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/P19_TBSVK P19_TBSVK]] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).
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[https://www.uniprot.org/uniprot/P19_TBSVK P19_TBSVK] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).
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==See Also==
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*[[P19|P19]]
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*[[RNA silencing suppressor|RNA silencing suppressor]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Tbsv]]
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[[Category: Large Structures]]
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[[Category: Malinina, L]]
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[[Category: Tomato bushy stunt virus]]
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[[Category: Popov, A N]]
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[[Category: Malinina L]]
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[[Category: Tamjar, J]]
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[[Category: Popov AN]]
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[[Category: Dimer]]
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[[Category: Tamjar J]]
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[[Category: Rna binding protein-rna complex]]
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[[Category: Rna silencing suppression]]
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[[Category: Trinucleotide repeat]]
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Revision as of 21:30, 16 November 2022

Crystal structure of p19 in complex with double-helical 19mer RNA p(CAG)3C(CUG)3

PDB ID 4j39

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