4v0s
From Proteopedia
(Difference between revisions)
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==Crystal structure of Mycobacterium tuberculosis Type II Dehydroquinase D88N mutant inhibited by a 3-dehydroquinic acid derivative== | ==Crystal structure of Mycobacterium tuberculosis Type II Dehydroquinase D88N mutant inhibited by a 3-dehydroquinic acid derivative== | ||
| - | <StructureSection load='4v0s' size='340' side='right' caption='[[4v0s]], [[Resolution|resolution]] 1.55Å' scene=''> | + | <StructureSection load='4v0s' size='340' side='right'caption='[[4v0s]], [[Resolution|resolution]] 1.55Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4v0s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V0S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V0S FirstGlance]. <br> | <table><tr><td colspan='2'>[[4v0s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V0S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V0S FirstGlance]. <br> | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/AROQ_MYCTO AROQ_MYCTO]] Catalyzes a trans-dehydration via an enolate intermediate. | [[http://www.uniprot.org/uniprot/AROQ_MYCTO AROQ_MYCTO]] Catalyzes a trans-dehydration via an enolate intermediate. | ||
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| + | ==See Also== | ||
| + | *[[Dehydroquinase 3D structures|Dehydroquinase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: 3-dehydroquinate dehydratase]] | [[Category: 3-dehydroquinate dehydratase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Gonzalez-Bello, C]] | [[Category: Gonzalez-Bello, C]] | ||
[[Category: Hawkins, A R]] | [[Category: Hawkins, A R]] | ||
Revision as of 10:56, 26 February 2020
Crystal structure of Mycobacterium tuberculosis Type II Dehydroquinase D88N mutant inhibited by a 3-dehydroquinic acid derivative
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Categories: 3-dehydroquinate dehydratase | Large Structures | Gonzalez-Bello, C | Hawkins, A R | Lamb, H | Llamas-Saiz, A L | Maneiro, M | Otero, J M | Peon, A | Raaij, M J.van | Santiago, C | Binding site | Inhibitor | Lyase | Protein binding | Shikimis acid pathway | Substrate specificity | Type 2 dehydroquinase
