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5nxs
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Human Pro-myostatin Precursor at 4.2 A Resolution with Experimental Phases from SeMet labelling== | ==Crystal Structure of Human Pro-myostatin Precursor at 4.2 A Resolution with Experimental Phases from SeMet labelling== | ||
| - | <StructureSection load='5nxs' size='340' side='right' caption='[[5nxs]], [[Resolution|resolution]] 4.19Å' scene=''> | + | <StructureSection load='5nxs' size='340' side='right'caption='[[5nxs]], [[Resolution|resolution]] 4.19Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5nxs]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5nxs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NXS FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.19Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nxs OCA], [https://pdbe.org/5nxs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nxs RCSB], [https://www.ebi.ac.uk/pdbsum/5nxs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nxs ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/GDF8_HUMAN GDF8_HUMAN] Myostatin-related muscle hypertrophy. The disease is caused by mutations affecting the gene represented in this entry. |
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/GDF8_HUMAN GDF8_HUMAN] Acts specifically as a negative regulator of skeletal muscle growth. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5nxs" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5nxs" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Growth differentiation factor 3D STRUCTURES|Growth differentiation factor 3D STRUCTURES]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Cotton TR]] |
| - | [[Category: | + | [[Category: Fischer G]] |
| - | [[Category: | + | [[Category: Hyvonen M]] |
| - | + | ||
| - | + | ||
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Current revision
Crystal Structure of Human Pro-myostatin Precursor at 4.2 A Resolution with Experimental Phases from SeMet labelling
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