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(Crystal structure of the µ-opioid receptor bound to a morphinan antagonist)
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Investigate the structure after loading the <jmol><jmollink><text>Figure 1 model</text><script>exit;SCRIPT "http://proteopedia.org/wiki/images/2/20/Nature10954Fig1aLeft_4dkl-2.png"</script></jmollink></jmol> by dragging it around using your mouse or clicking the buttons below. SHIFT-drag to zoom.
Investigate the structure after loading the <jmol><jmollink><text>Figure 1 model</text><script>exit;SCRIPT "http://proteopedia.org/wiki/images/2/20/Nature10954Fig1aLeft_4dkl-2.png"</script></jmollink></jmol> by dragging it around using your mouse or clicking the buttons below. SHIFT-drag to zoom.
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<jmol><jmollink><text>(a) exocellular view</text><script>SCRIPT http://proteopedia.org/wiki/images/0/00/Nature10954_fig1d.spt('top')</script></jmollink></jmol>
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<jmol><jmollink><text>(a) exocellular view</text><script>if (!figure){figure="http://proteopedia.org/wiki/images/2/20/Nature10954Fig1aLeft_4dkl-2.png";SCRIPT @figure}; SCRIPT http://proteopedia.org/wiki/images/0/00/Nature10954_fig1d.spt('top')</script></jmollink></jmol>
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<jmol><jmollink><text>(b) endocellular</text><script>SCRIPT http://proteopedia.org/wiki/images/0/00/Nature10954_fig1d.spt('bottom')</script></jmollink></jmol>
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<jmol><jmollink><text>(b) endocellular</text><script>if (!figure){figure="http://proteopedia.org/wiki/images/2/20/Nature10954Fig1aLeft_4dkl-2.png";SCRIPT @figure};SCRIPT http://proteopedia.org/wiki/images/0/00/Nature10954_fig1d.spt('bottom')</script></jmollink></jmol>
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<jmol><jmollink><text>(c) trans-membrane view</text><script>SCRIPT http://proteopedia.org/wiki/images/0/00/Nature10954_fig1d.spt('side')</script></jmollink></jmol>
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<jmol><jmollink><text>(c) trans-membrane view</text><script>if (!figure){figure="http://proteopedia.org/wiki/images/2/20/Nature10954Fig1aLeft_4dkl-2.png";SCRIPT @figure};SCRIPT http://proteopedia.org/wiki/images/0/00/Nature10954_fig1d.spt('side')</script></jmollink></jmol>
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<jmol><jmollink><text>(d) trans-membrane view with abstract membrane</text><script>SCRIPT http://proteopedia.org/wiki/images/0/00/Nature10954_fig1d.spt('draw')</script></jmollink></jmol>
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<jmol><jmollink><text>(d) trans-membrane view with abstract membrane</text><script>if (!figure){figure="http://proteopedia.org/wiki/images/2/20/Nature10954Fig1aLeft_4dkl-2.png";SCRIPT @figure};SCRIPT http://proteopedia.org/wiki/images/0/00/Nature10954_fig1d.spt('draw')</script></jmollink></jmol>
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</StructureSection>
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<jmol><jmollink><text>Animate Figure 1a</text><script>script "http://proteopedia.org/wiki/images/1/1f/Nature10954_fig1a.spt"</script></jmollink></jmol>
 
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code for the above (space inserted just after the : <code>&lt;jmol><jmollink><text>View Figure 1a: Overall view of the µ-OR structure</text><script>exit;figure=1;SCRIPT "/wiki/images/8/8b/4dkl-local-contact.png"</script></jmollink></jmol></code>
code for the above (space inserted just after the : <code>&lt;jmol><jmollink><text>View Figure 1a: Overall view of the µ-OR structure</text><script>exit;figure=1;SCRIPT "/wiki/images/8/8b/4dkl-local-contact.png"</script></jmollink></jmol></code>
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<jmol><jmollink><text>Animate Figure 1a</text><script>script "http://proteopedia.org/wiki/images/1/1f/Nature10954_fig1a.spt"</script></jmollink></jmol>
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Revision as of 12:24, 30 January 2018

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

[https://www.nature.com/articles/nature10954 Nature volume 485, pages 321–326 (17 May 2012) doi:10.1038/nature10954]

Click a green link on the left to load Figure 1

Drag the structure with the mouse to rotate


BELOW THIS LINE IS NOT PART OF THE ACTUAL PAGE

code for the above (space inserted just after the : <jmol><jmollink><text>View Figure 1a: Overall view of the µ-OR structure</text><script>exit;figure=1;SCRIPT "/wiki/images/8/8b/4dkl-local-contact.png"</script></jmollink></jmol>





is a close-up view of a  bound to the µ-opioid receptor. The green circles indicate hydrogen bonds. 
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