5m8c
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Spliceosome component== | |
| - | + | <StructureSection load='5m8c' size='340' side='right' caption='[[5m8c]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5m8c]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M8C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M8C FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RING-type_E3_ubiquitin_transferase RING-type E3 ubiquitin transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.27 2.3.2.27] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m8c OCA], [http://pdbe.org/5m8c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m8c RCSB], [http://www.ebi.ac.uk/pdbsum/5m8c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m8c ProSAT]</span></td></tr> |
| - | [[Category: Moura, T | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PRP19_YEAST PRP19_YEAST]] Involved in pre-mRNA splicing. Acts a central component of the NTC complex (or PRP19-associated complex) that associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation. Involved in DNA repair. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: RING-type E3 ubiquitin transferase]] | ||
| + | [[Category: Moura, T R]] | ||
[[Category: Pena, V]] | [[Category: Pena, V]] | ||
| + | [[Category: Spliceosome]] | ||
| + | [[Category: Splicing]] | ||
Revision as of 06:12, 28 February 2018
Spliceosome component
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