5z4m
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of TailorD343A with bound UTP and Mg== | |
| - | + | <StructureSection load='5z4m' size='340' side='right' caption='[[5z4m]], [[Resolution|resolution]] 1.74Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5z4m]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z4M FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_uridylyltransferase RNA uridylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.52 2.7.7.52] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z4m OCA], [http://pdbe.org/5z4m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z4m RCSB], [http://www.ebi.ac.uk/pdbsum/5z4m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z4m ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TUTT_DROME TUTT_DROME]] Uridylyltransferase which mediates terminal uridylation of miRNAs, leading to their degradation. Has high specificity for splicing-derived miRNAs (mirtrons) and other miRNA substrates containing a 3'-G terminal nucleotide. Appears to be a major suppressor of mirtron biogenesis.<ref>PMID:26145174</ref> <ref>PMID:26145176</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: RNA uridylyltransferase]] | ||
[[Category: Cheng, L]] | [[Category: Cheng, L]] | ||
| - | [[Category: Yu, H]] | ||
[[Category: Gong, Q]] | [[Category: Gong, Q]] | ||
| + | [[Category: Jiang, Y]] | ||
| + | [[Category: Li, F]] | ||
[[Category: Shi, Y]] | [[Category: Shi, Y]] | ||
| - | [[Category: Jiang, Y]] | ||
[[Category: Xie, C]] | [[Category: Xie, C]] | ||
| - | [[Category: | + | [[Category: Yu, H]] |
| + | [[Category: Terminal uridylyltransferase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 06:45, 31 October 2018
Structure of TailorD343A with bound UTP and Mg
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