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1tlo

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==High resolution crystal structure of calpain I protease core in complex with E64==
==High resolution crystal structure of calpain I protease core in complex with E64==
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<StructureSection load='1tlo' size='340' side='right' caption='[[1tlo]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='1tlo' size='340' side='right'caption='[[1tlo]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1tlo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TLO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TLO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1tlo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TLO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1TLO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=E64:N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE'>E64</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=E64:N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE'>E64</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kxr|1kxr]], [[1mdw|1mdw]], [[1dfo|1dfo]], [[1kfu|1kfu]], [[1kfx|1kfx]], [[1nx0|1nx0]], [[1tl9|1tl9]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1kxr|1kxr]], [[1mdw|1mdw]], [[1dfo|1dfo]], [[1kfu|1kfu]], [[1kfx|1kfx]], [[1nx0|1nx0]], [[1tl9|1tl9]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAPN1, CLS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAPN1, CLS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calpain-1 Calpain-1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.52 3.4.22.52] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calpain-1 Calpain-1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.52 3.4.22.52] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tlo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tlo OCA], [http://pdbe.org/1tlo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tlo RCSB], [http://www.ebi.ac.uk/pdbsum/1tlo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tlo ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1tlo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tlo OCA], [http://pdbe.org/1tlo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tlo RCSB], [http://www.ebi.ac.uk/pdbsum/1tlo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tlo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 1tlo" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1tlo" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Calpain 3D structures|Calpain 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Buffalo rat]]
[[Category: Buffalo rat]]
[[Category: Calpain-1]]
[[Category: Calpain-1]]
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[[Category: Large Structures]]
[[Category: Campbell, R L]]
[[Category: Campbell, R L]]
[[Category: Cuerrier, D]]
[[Category: Cuerrier, D]]

Revision as of 11:55, 24 December 2020

High resolution crystal structure of calpain I protease core in complex with E64

PDB ID 1tlo

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