4lls

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==Crystal structure of a farnesyl diphosphate synthase from Roseobacter denitrificans OCh 114, target EFI-509393, with IPP, GSPP, and calcium bound in active site==
==Crystal structure of a farnesyl diphosphate synthase from Roseobacter denitrificans OCh 114, target EFI-509393, with IPP, GSPP, and calcium bound in active site==
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<StructureSection load='4lls' size='340' side='right' caption='[[4lls]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='4lls' size='340' side='right'caption='[[4lls]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4lls]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Erythrobacter_sp._(strain_och_114) Erythrobacter sp. (strain och 114)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LLS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LLS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4lls]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Roseobacter_denitrificans_OCh_114 Roseobacter denitrificans OCh 114]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LLS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LLS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GST:GERANYL+S-THIOLODIPHOSPHATE'>GST</scene>, <scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GST:GERANYL+S-THIOLODIPHOSPHATE'>GST</scene>, <scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4llt|4llt]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lls FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lls OCA], [https://pdbe.org/4lls PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lls RCSB], [https://www.ebi.ac.uk/pdbsum/4lls PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lls ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ispA, RD1_0549 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=375451 Erythrobacter sp. (strain OCh 114)])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(2E,6E)-farnesyl_diphosphate_synthase (2E,6E)-farnesyl diphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.10 2.5.1.10] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lls FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lls OCA], [http://pdbe.org/4lls PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lls RCSB], [http://www.ebi.ac.uk/pdbsum/4lls PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lls ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q16CN9_ROSDO Q16CN9_ROSDO]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Almo, S C]]
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[[Category: Large Structures]]
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[[Category: Bhosle, R]]
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[[Category: Roseobacter denitrificans OCh 114]]
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[[Category: Chowdhury, S]]
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[[Category: Al Obaidi NF]]
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[[Category: EFI, Enzyme Function Initiative]]
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[[Category: Almo SC]]
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[[Category: Evans, B]]
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[[Category: Bhosle R]]
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[[Category: Gerlt, J A]]
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[[Category: Chowdhury S]]
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[[Category: Glenn, A Scott]]
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[[Category: Evans B]]
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[[Category: Hammonds, J]]
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[[Category: Gerlt JA]]
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[[Category: Hillerich, B]]
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[[Category: Hammonds J]]
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[[Category: Imker, H J]]
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[[Category: Hillerich B]]
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[[Category: Kim, J]]
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[[Category: Imker HJ]]
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[[Category: Love, J]]
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[[Category: Kim J]]
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[[Category: Morisco, L L]]
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[[Category: Love J]]
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[[Category: Obaidi, N F.Al]]
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[[Category: Morisco LL]]
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[[Category: Seidel, R D]]
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[[Category: Scott Glenn A]]
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[[Category: Sojitra, S]]
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[[Category: Seidel RD]]
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[[Category: Stead, M]]
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[[Category: Sojitra S]]
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[[Category: Toro, R]]
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[[Category: Stead M]]
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[[Category: Washington, E]]
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[[Category: Toro R]]
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[[Category: Wasserman, S R]]
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[[Category: Washington E]]
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[[Category: Enzyme function initiative]]
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[[Category: Wasserman SR]]
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[[Category: Polyprenyl synthetase]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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Revision as of 11:09, 14 December 2022

Crystal structure of a farnesyl diphosphate synthase from Roseobacter denitrificans OCh 114, target EFI-509393, with IPP, GSPP, and calcium bound in active site

PDB ID 4lls

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