Sandbox Reserved 1407
From Proteopedia
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This protein originated in tarantulas, Red Junglefowls and humans. | This protein originated in tarantulas, Red Junglefowls and humans. | ||
== Protein Structure == | == Protein Structure == | ||
| - | Heavy meromyosin (HMM) is a subunit of myosin. There are two fragments that make up HMM: S-1 and S-2. S-1 projects out on an angle whereas S-2 is comprised of globular heads that can bind to actin. Together, these are called a myosin cross bridge. There are four distinct macromolecules that comprise HMM, including Myosin II regulatory light chain (196 amino acids: magenta), <scene name='77/777727/Heavy_meroyosin_c_d/ | + | Heavy meromyosin (HMM) is a subunit of myosin. There are two fragments that make up HMM: S-1 and S-2. S-1 projects out on an angle whereas S-2 is comprised of globular heads that can bind to actin. Together, these are called a myosin cross bridge. There are four distinct macromolecules that comprise HMM, including Myosin II regulatory light chain (196 amino acids: magenta), <scene name='77/777727/Heavy_meroyosin_c_d/3'>Myosin light polypeptide 6</scene> (150 amino acids: blue), Myosin 11; Myosin-7 (971 amino acids: gold), and Myosin 7; Myosin 11 (973 amino acids: purple). |
== Function == | == Function == | ||
Heavy meromyosin is a part of the actin-myosin system. Heavy meromyosin (and light meromyosin) are subunits of myosin. HMM is the globular head portion of myosin which determines the rate of muscle contraction in an organism. Actin binding capacity and ATPase activity are dependent on HMM. | Heavy meromyosin is a part of the actin-myosin system. Heavy meromyosin (and light meromyosin) are subunits of myosin. HMM is the globular head portion of myosin which determines the rate of muscle contraction in an organism. Actin binding capacity and ATPase activity are dependent on HMM. | ||
Revision as of 21:09, 12 February 2018
| This Sandbox is Reserved from January through July 31, 2018 for use in the course HLSC322: Principles of Genetics and Genomics taught by Genevieve Houston-Ludlam at the University of Maryland, College Park, USA. This reservation includes Sandbox Reserved 1311 through Sandbox Reserved 1430. |
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Heavy Meromyosin
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References
https://www.ncbi.nlm.nih.gov/pubmed/27591903
https://www.ncbi.nlm.nih.gov/books/NBK9961/
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/heavy-meromyosin
