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1ot7

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==Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR==
==Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR==
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<StructureSection load='1ot7' size='340' side='right' caption='[[1ot7]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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<StructureSection load='1ot7' size='340' side='right'caption='[[1ot7]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ot7]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OT7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OT7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ot7]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OT7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1OT7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHC:6-ETHYL-CHENODEOXYCHOLIC+ACID'>CHC</scene>, <scene name='pdbligand=IU5:ISO-URSODEOXYCHOLIC+ACID'>IU5</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CHC:6-ETHYL-CHENODEOXYCHOLIC+ACID'>CHC</scene>, <scene name='pdbligand=IU5:ISO-URSODEOXYCHOLIC+ACID'>IU5</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1osv|1osv]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1osv|1osv]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR1H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR1H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ot7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ot7 OCA], [http://pdbe.org/1ot7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ot7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ot7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ot7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1ot7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ot7 OCA], [http://pdbe.org/1ot7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ot7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ot7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ot7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 1ot7" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1ot7" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Bile acid receptor 3D structures|Bile acid receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Buffalo rat]]
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[[Category: Large Structures]]
[[Category: Devarakonda, S]]
[[Category: Devarakonda, S]]
[[Category: Han, Q]]
[[Category: Han, Q]]

Revision as of 07:14, 9 December 2020

Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR

PDB ID 1ot7

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