Sandbox Reserved 1322
From Proteopedia
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{{Sandbox_Reserved_HLSC322}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | {{Sandbox_Reserved_HLSC322}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | ||
| - | == | + | ==Humanized Acetylcholine Binding Protein and Lobeline Complex== |
<StructureSection load='5ouh' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='5ouh' size='340' side='right' caption='Caption for this structure' scene=''> | ||
| - | + | Acetylcholine Binding Protein modulates synaptic transmission of acetylcholine in snails. The humanized version consists of a complex with Lobeline. | |
== Function == | == Function == | ||
| - | + | Lobeline by itself can either activate or inhibit nicotinic acetylcholine receptors in the both CNS and PNS. Acetylcholine Binding Protein, on the other hand, binds acetylcholine, modulating its transmission through ligand-gated ion channels. Combined with Lobeline, this can cause a significant decrease in the activity of acetylcholine receptors by inhibiting receptor activity while also modulating transmission through such receptors. | |
== Disease == | == Disease == | ||
| - | + | The protein is associated with Alzheimer's Disease and Schizophrenia. | |
== Relevance == | == Relevance == | ||
Revision as of 20:43, 20 February 2018
| This Sandbox is Reserved from January through July 31, 2018 for use in the course HLSC322: Principles of Genetics and Genomics taught by Genevieve Houston-Ludlam at the University of Maryland, College Park, USA. This reservation includes Sandbox Reserved 1311 through Sandbox Reserved 1430. |
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Humanized Acetylcholine Binding Protein and Lobeline Complex
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