This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Sandbox Reserved 1311

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 12: Line 12:
===Function===
===Function===
General Function: Low-density lipoprotein particle receptor binding
General Function: Low-density lipoprotein particle receptor binding
 +
Specific Function: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.<ref>https://pubchem.ncbi.nlm.nih.gov/compound/phosphocholine</ref>
Specific Function: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.<ref>https://pubchem.ncbi.nlm.nih.gov/compound/phosphocholine</ref>
===Properties===
===Properties===
Molecular Weight: 184.152 g/mol
Molecular Weight: 184.152 g/mol
 +
Biofluid Locations: blood, breast milk, cerebrospinal fluid, saliva, urine
Biofluid Locations: blood, breast milk, cerebrospinal fluid, saliva, urine
 +
Tissue Locations: Brain, Epidermis, Fibroblasts, Intestine, Kidney, Liver, Placenta, Platelet, Stratum Corneum
Tissue Locations: Brain, Epidermis, Fibroblasts, Intestine, Kidney, Liver, Placenta, Platelet, Stratum Corneum
 +
Cellular location: cytoplasm, exosomes
Cellular location: cytoplasm, exosomes
 +
Target: CRP <ref> https://pubchem.ncbi.nlm.nih.gov/compound/phosphocholine </ref>
Target: CRP <ref> https://pubchem.ncbi.nlm.nih.gov/compound/phosphocholine </ref>

Revision as of 21:18, 20 February 2018

This Sandbox is Reserved from January through July 31, 2018 for use in the course HLSC322: Principles of Genetics and Genomics taught by Genevieve Houston-Ludlam at the University of Maryland, College Park, USA. This reservation includes Sandbox Reserved 1311 through Sandbox Reserved 1430.
To get started:
  • Click the edit this page tab at the top. Save the page after each step, then edit it again.
  • Click the 3D button (when editing, above the wikitext box) to insert Jmol.
  • show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
  • Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc.

More help: Help:Editing

HUMAN C-REACTIVE PROTEIN COMPLEXED WITH PHOSPHOCHOLINE

Caption for this structure

Drag the structure with the mouse to rotate

References

  1. https://www.ncbi.nlm.nih.gov/gene/1401
  2. https://pubchem.ncbi.nlm.nih.gov/compound/phosphocholine
  3. https://pubchem.ncbi.nlm.nih.gov/compound/phosphocholine
Personal tools