Sandbox Reserved 1336
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
| - | This protein prefers to form homodimers, which means that the complex is made of two identical chains of itself. <scene name='77/777656/Singlechain/1'>Click here to see one chain | + | This protein prefers to form homodimers, which means that the complex is made of two identical chains of itself. <scene name='77/777656/Singlechain/1'>Click here to see one chain.</scene> |
There are multiple sites where calcium ions can bind. <scene name='77/777656/Ca_binding_sites/1'>Click here to see where these are.</scene> | There are multiple sites where calcium ions can bind. <scene name='77/777656/Ca_binding_sites/1'>Click here to see where these are.</scene> | ||
Revision as of 21:25, 20 February 2018
Contents |
Structure
|
Function
Platlet formation/clotting
Phospholipid movement
Apoptosis
Disease
Scott syndrome is a rare human disease caused by a mutation that affects TMEM16 proteins and results in the inability of platelets and other hematopoietic cells to bring phosphatidylserine to the surface for proper coagulation.
Relevance
Structural highlights
This protein prefers to form homodimers, which means that the complex is made of two identical chains of itself.
There are multiple sites where calcium ions can bind.
Once Ca ions bind to these sites, the chloride channel can open.
