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5nr8

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==Crystal structure of human chitotriosidase-1 (hCHIT) catalytic domain in complex with compound 7a==
==Crystal structure of human chitotriosidase-1 (hCHIT) catalytic domain in complex with compound 7a==
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<StructureSection load='5nr8' size='340' side='right' caption='[[5nr8]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
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<StructureSection load='5nr8' size='340' side='right'caption='[[5nr8]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5nr8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NR8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NR8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5nr8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NR8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NR8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=95N:1-(3-azanyl-1~{H}-1,2,4-triazol-5-yl)-~{N}-[2-(4-bromophenyl)ethyl]-~{N}-methyl-piperidin-4-amine'>95N</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=95N:1-(3-azanyl-1~{H}-1,2,4-triazol-5-yl)-~{N}-[2-(4-bromophenyl)ethyl]-~{N}-methyl-piperidin-4-amine'>95N</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHIT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nr8 OCA], [http://pdbe.org/5nr8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nr8 RCSB], [http://www.ebi.ac.uk/pdbsum/5nr8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nr8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nr8 OCA], [http://pdbe.org/5nr8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nr8 RCSB], [http://www.ebi.ac.uk/pdbsum/5nr8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nr8 ProSAT]</span></td></tr>
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</div>
</div>
<div class="pdbe-citations 5nr8" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5nr8" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Chitinase 3D structures|Chitinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Chitinase]]
[[Category: Chitinase]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Fadel, F]]
[[Category: Fadel, F]]
[[Category: Golebiowski, A]]
[[Category: Golebiowski, A]]
[[Category: Podjarny, A]]
[[Category: Podjarny, A]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 06:46, 16 October 2019

Crystal structure of human chitotriosidase-1 (hCHIT) catalytic domain in complex with compound 7a

PDB ID 5nr8

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