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| - | | + | #REDIRECT [[6e7f]] This PDB entry is obsolete and replaced by 6e7f |
| - | ==Crystal Structure of Human Inositol Polyphosphate Multikinase (IPMK) Catalytic Core Domain==
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| - | <StructureSection load='6c8a' size='340' side='right' caption='[[6c8a]], [[Resolution|resolution]] 2.90Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[6c8a]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C8A FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inositol-polyphosphate_multikinase Inositol-polyphosphate multikinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.151 2.7.1.151] </span></td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6c8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c8a OCA], [http://pdbe.org/6c8a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c8a RCSB], [http://www.ebi.ac.uk/pdbsum/6c8a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c8a ProSAT]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[http://www.uniprot.org/uniprot/IPMK_HUMAN IPMK_HUMAN]] Inositol phosphate kinase with a broad substrate specificity. Has a preference for inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4).<ref>PMID:12027805</ref> <ref>PMID:12223481</ref>
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| - | == References ==
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| - | <references/>
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Inositol-polyphosphate multikinase]]
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| - | [[Category: Blind, R]]
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| - | [[Category: Seacrist, C]]
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| - | [[Category: Inositol phosphate]]
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| - | [[Category: Ipmk]]
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| - | [[Category: Kinase]]
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| - | [[Category: Transferase]]
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