2es4

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[[Image:2es4.gif|left|200px]]
[[Image:2es4.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2es4 |SIZE=350|CAPTION= <scene name='initialview01'>2es4</scene>, resolution 1.85&Aring;
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The line below this paragraph, containing "STRUCTURE_2es4", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Triacylglycerol_lipase Triacylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= lifO, lipB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=337 Burkholderia glumae])
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-->
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|DOMAIN=
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{{STRUCTURE_2es4| PDB=2es4 | SCENE= }}
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|RELATEDENTRY=[[1cvl|1CVL]], [[1tah|1TAH]], [[1qge|1QGE]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2es4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2es4 OCA], [http://www.ebi.ac.uk/pdbsum/2es4 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2es4 RCSB]</span>
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}}
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'''Crystal structure of the Burkholderia glumae lipase-specific foldase in complex with its cognate lipase'''
'''Crystal structure of the Burkholderia glumae lipase-specific foldase in complex with its cognate lipase'''
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[[Category: Tommassen, J.]]
[[Category: Tommassen, J.]]
[[Category: Wyns, L.]]
[[Category: Wyns, L.]]
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[[Category: a/b hydrolase fold]]
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[[Category: A/b hydrolase fold]]
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[[Category: all alpha helix protein]]
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[[Category: All alpha helix protein]]
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[[Category: extensive interaction area]]
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[[Category: Extensive interaction area]]
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[[Category: protein-protein complex]]
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[[Category: Protein-protein complex]]
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[[Category: steric chaperone]]
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[[Category: Steric chaperone]]
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[[Category: triacylglycerol hydrolase]]
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[[Category: Triacylglycerol hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 03:03:12 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:53:04 2008''
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Revision as of 00:03, 4 May 2008

Image:2es4.gif

Template:STRUCTURE 2es4

Crystal structure of the Burkholderia glumae lipase-specific foldase in complex with its cognate lipase


Overview

Secretion via the type II secretion pathway in Gram-negative bacteria often relies crucially on steric chaperones in the periplasm. Here, we report the crystal structure of the soluble form of a lipase-specific foldase (Lif) from Burkholderia glumae in complex with its cognate lipase. The structure reveals how Lif uses a novel alpha-helical scaffold to embrace lipase, thereby creating an unusually extensive folding platform.

About this Structure

2ES4 is a Protein complex structure of sequences from Burkholderia glumae. Full crystallographic information is available from OCA.

Reference

Structure of a membrane-based steric chaperone in complex with its lipase substrate., Pauwels K, Lustig A, Wyns L, Tommassen J, Savvides SN, Van Gelder P, Nat Struct Mol Biol. 2006 Apr;13(4):374-5. Epub 2006 Mar 5. PMID:16518399 Page seeded by OCA on Sun May 4 03:03:12 2008

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