This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5qc1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Crystal structure of human Cathepsin-S with bound ligand==
==Crystal structure of human Cathepsin-S with bound ligand==
-
<StructureSection load='5qc1' size='340' side='right' caption='[[5qc1]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
+
<StructureSection load='5qc1' size='340' side='right'caption='[[5qc1]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5qc1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QC1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QC1 FirstGlance]. <br>
+
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QC1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QC1 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B9S:(2S)-1-(4,4-dimethylpiperidin-1-yl)-3-{3-[3-({[(4-fluorophenyl)methyl]amino}methyl)-4-(trifluoromethyl)phenyl]-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl}propan-2-ol'>B9S</scene></td></tr>
+
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qc1 OCA], [https://pdbe.org/5qc1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qc1 RCSB], [https://www.ebi.ac.uk/pdbsum/5qc1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qc1 ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTSS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qc1 OCA], [http://pdbe.org/5qc1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qc1 RCSB], [http://www.ebi.ac.uk/pdbsum/5qc1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qc1 ProSAT]</span></td></tr>
+
</table>
</table>
-
== Function ==
+
 
-
[[http://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
+
==See Also==
 +
*[[Cathepsin 3D structures|Cathepsin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Cathepsin S]]
+
[[Category: Large Structures]]
-
[[Category: Human]]
+
[[Category: Ameriks MK]]
-
[[Category: Ameriks, M K]]
+
[[Category: Bembenek SD]]
-
[[Category: Bembenek, S D]]
+
[[Category: Burley SK]]
-
[[Category: Burley, S K]]
+
[[Category: Mirzadegan T]]
-
[[Category: Mirzadegan, T]]
+
[[Category: Shao C]]
-
[[Category: Shao, C]]
+
[[Category: Yang H]]
-
[[Category: Yang, H]]
+
-
[[Category: Cathepsin s]]
+
-
[[Category: D3r]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Ligand docking]]
+

Revision as of 14:05, 17 November 2021

Crystal structure of human Cathepsin-S with bound ligand

PDB ID 5qc1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5qc1"
Personal tools