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This is a default text for your page '. Click above on edit this page' to modify. Be careful with the < and > signs. You may include any references to papers as in: the use of JSmol in Proteopedia ^[1] or to the article describing Jmol ^[2] to the rescue.

Function

Protein binding:Selectively binds to other protein complexes non-covalently. Angiogenin promotes angiogenesis which is a stimulator of new blood vessels. While RNASE1 works to inhibit an endonuclease that cleaves phosphodiester bonds, and RNASE2 .

Disease

has a role in cancers and tumor growth. A mutation in 1a4y which results in increased activity of Ang could lead to tumor growth. Ang has also been theorized as a protector of the central nervous system and thus under-production of 1a4y may result in limited Ang and thus neurodegenerative diseases.

Relevance

Structural highlights

-The unusual non-globular structure of ribonuclease inhibitor, its solvent parallel Beta-sheet and the conformational flexibility of the structure are used in the interaction. These structures make the ribonuclease inhibitor an effective binding protein. Ribonuclease inhibitor is encoded by the gene RNH1. Angiogenin- Encoded for by the ANG gene. This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.